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Chapter – 2 Microwave assisted simple and fast…..
2.6 SPECTRAL DISCUSSION
2.6.1 MASS SPECTRAL STUDY
Mass spectra of the synthesized compounds were recorded on
Shimadzu GC-MS QP-2010 model using direct injection probe technique.
The molecular ion peak was found in agreement with molecular weight of the
respective compound. Characteristic M +2 ion peaks with one-third intensity of
molecular ion peak were observed in case of compounds having chlorine
atom. Fragmentation pattern can be observed to be particular for these
compounds and the characteristic peaks obtained for each compound.
Probable fragmentation pattern for DNJ-302, DNJ-402, DNJ-502 and DNJ-
602 can be discussed as under.
2-methyl-1-(3-morpholin-4-ylpropyl) indoline (DNJ-302)
1. The target compound showed characteristic molecular ion peak.
2. O1-C2 and O1-C6 bond cleavages gave characteristic peak at 245 m/e.
[1]
3. After O1-C2 and O1-C6 bond cleavages, C2-C3 bond cleavage gave
characteristic peak at 229 m/e. [2]
4. After C2-C3 bond cleavage, C5-C6 bond cleavage gave characteristic
peak at 223 m/e. [3]
5. After C5-C6 bond cleavage, C3-N4 bond cleavage and subsequently N4-
C5 bond cleavage gave two characteristic peaks at 208 m/e and 186
m/e respectively. [4] & [5]
6. After C3-N4 and N4-C5 bond cleavages, C7-N4 bond cleavage gave
characteristic peak at 172 m/e. [6]
7. After C7-N4 bond cleavage, C7-C8 and C8-C9 bond cleavages gave two
characteristic peaks at 158 m/e and 146 m/e (BASE PEAK). [7] & [8]
8. After C7-C8 and C8-C9 bond cleavages, C9-N10 and C11-C19 bond
cleavages gave two characteristic peaks at 130 m/e and 118 m/e. [9] &
[10]
Department of Chemistry, Saurashtra University, Rajkot – 360 005 88