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Content
CHAPTER – 2 MICROWAVE ASSISTED SIMPLE AND FAST N –
ALKYLATION OF 2-METHYL INDOLINE AND ISATIN
MOIETY
2.1 Aim of current work 73
2.2 Reaction scheme 75
2.3 Plausible reaction mechanism 77
2.4 Experimental 79
2.5 Physical data tables 84
2.6 Spectral discussion 88
2.6.1 Mass spectral study 88
2.6.2 IR spectral study 94
2.6.3 1 H NMR spectral study 95
2.6.4 Elemental analysis 97
2.7 Analytical data 98
2.8 Results and discussion 102
2.9 Conclusion 103
2.10 Spectral representation of synthesized compounds 104
PART – B STUDIES ON ISATIN DERIVATIVES
B.1 Introduction to isatin 113
B.2 Physical properties of isatin 114
B.3 Synthesis of isatin 114
B.4 N-alkylation on isatin 116
B.5 N-acylation on isatin 118
B.6 Mannich reaction on isatin 119
B.7 Biological activities associated with isatins 131
B.8 References 133
CHAPTER – 3 PREPARATION OF SMALL LIBRARY OF POTENTIAL
ANTICANCER AGENTS: SCHIFF BASES FROM ISATIN
CORE STRUCTURE
3.1 Aim of current work 148
Department of Chemistry, Saurashtra University, Rajkot – 360 005 2