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Chapter – 5 Synthesis and Characterization…..
3-[(4-ETHYL PIPERAZIN-1-YL) METHYL]-4-[(4-FLUORO PHENYL)
AMINO]-2H-CHROMEN-2-ONE (DNJ-1008): IR (KBr, cm -1 ): 3388 (-NH),
3080 (Ar-H, str), 2967 (-CH3), 2811 (-CH2), 1707 (>CO), 1607, 1584, 1500,
1470 (Ar-H, ben), 1335 (C-N, Ar, 3°), 1304 (C-N, Ar, 2°), 1061 (C-O-C), 992
(C-F), 819 (1,4-di sub); MS m/z = 381 (M + ); Anal. Calcd. for C22H24FN3O2: C,
69.27; H, 6.34; N, 11.02. Found: C, 69.28; H, 6.36; N, 11.04.
3-[(4-ETHYL PIPERAZIN-1-YL) METHYL]-4-[(2-METHYL PHENYL)
AMINO]-2H-CHROMEN-2-ONE (DNJ-1009): IR (KBr, cm -1 ): 3389 (-NH),
3079 (Ar-H, str), 2962 (-CH3), 2809 (-CH2), 1706 (>CO), 1607, 1584, 1500,
1470 (Ar-H, ben), 1338 (C-N, Ar, 3°), 1307 (C-N, Ar, 2°), 1069 (C-O-C), 755
(1,2-di sub); MS m/z = 377 (M + ); Anal. Calcd. for C23H27N3O2: C, 73.18; H,
7.21; N, 11.13. Found: C, 73.15; H, 7.24; N, 11.10.
3-[(4-ETHYL PIPERAZIN-1-YL) METHYL]-4-[(3-METHYL PHENYL)
AMINO]-2H-CHROMEN-2-ONE (DNJ-1010): IR (KBr, cm -1 ): 3388 (-NH),
3081 (Ar-H, str), 2962 (-CH3), 2811 (-CH2), 1707 (>CO), 1600, 1575, 1481,
1465 (Ar-H, ben), 1338 (C-N, Ar, 3°), 1307 (C-N, Ar, 2°), 1072 (C-O-C), 775
(1,3-di sub); MS m/z = 377 (M + ); Anal. Calcd. for C23H27N3O2: C, 73.18; H,
7.21; N, 11.13. Found: C, 73.20; H, 7.24; N, 11.10.
3-[(4-ETHYL PIPERAZIN-1-YL) METHYL]-4-[(2-METHOXY PHENYL)
AMINO]-2H-CHROMEN-2-ONE (DNJ-1011): IR (KBr, cm -1 ): 3380 (-NH),
3070 (Ar-H, str), 2967 (-CH3), 2809 (-CH2), 1705 (>CO), 1600, 1584, 1507,
1470 (Ar-H, ben), 1337 (C-N, Ar, 3°), 1305 (C-N, Ar, 2°), 1051 (C-O-C), 758
(1,2-di sub); MS m/z = 393 (M + ); Anal. Calcd. for C23H27N3O3: C, 70.21; H,
6.92; N, 10.68. Found: C, 70.19; H, 6.95; N, 10.71.
3-[(4-ETHYL PIPERAZIN-1-YL) METHYL]-4-[(3-METHOXY PHENYL)
AMINO]-2H-CHROMEN-2-ONE (DNJ-1012): IR (KBr, cm -1 ): 3388 (-NH),
3080 (Ar-H, str), 2967 (-CH3), 2811 (-CH2), 1707 (>CO), 1602, 1580, 1483,
1469 (Ar-H, ben), 1336 (C-N, Ar, 3°), 1307 (C-N, Ar, 2°), 1070 (C-O-C), 780
(1,3-di sub); MS m/z = 393 (M + ); Anal. Calcd. for C23H27N3O3: C, 70.21; H,
6.92; N, 10.68. Found: C, 70.20; H, 6.95; N, 10.67.
Department of Chemistry, Saurashtra University, Rajkot – 360 005 310