Download (4Mb) - Etheses - Saurashtra University

Content
3.2 Reaction scheme 149
3.3 Plausible reaction mechanism 152
3.4 Experimental 154
3.5 Physical data tables 159
3.6 Spectral discussion 162
3.6.1 Mass spectral study 162
3.6.2 IR spectral study 166
3.6.3 1 H & 13 C NMR spectral study 167
3.6.4 Elemental analysis 171
3.7 Analytical data 172
3.8 Results and discussion 176
3.9 Conclusion 177
3.10 Spectral representation of synthesized compounds 178
CHAPTER – 4 STUDIES ON DIFFERENT TYPES OF REACTIONS ON
PYRAZOLE CORE STRUCTURE
4.1 Introduction to pyrazole aldehydes 188
4.2 Introduction to oxindole 190
4.2.1 Physical properties of oxindole 190
4.2.2 Synthesis of oxindole 191
4.2.3 Synthetic oxindoles as enzyme inhibitors 193
4.3 Introduction to coumarin 199
4.3.1 Synthesis of 4-hydroxycoumarin 199
4.3.2 Biological activities associated with 4-hydroxycoumarin
derivatives 200
4.3.3 Introduction to coumarinyl chalcones 201
4.3.4 Chalcones of 3-acetyl-4-hydroyxcoumarin 205
4.4 Introduction to chromane diones 208
4.5 Use of 4-hydroxycoumarin in dihydropyrimidine synthesis 213
4.6 Aim of current work 216
4.7 Reaction scheme 218
4.8 Plausible reaction mechanism 222
4.9 Experimental 224
Department of Chemistry, Saurashtra University, Rajkot – 360 005 3