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Chapter – 4 Studies on different types of reactions…..
DNJ-1601 to DNJ-1605 and DNJ-1701 to DNJ-1705 serieses of
compounds, almost similar kind of frequencies were observed. Stretching
frequency for secondary amine group (-NH) was obtained near 3150 cm -1 in
all the compounds. Stretching and bending frequency for aromatic and
stretching frequencies for methyl, methylene groups were found near 3050
cm -1 , 1400-1640 cm -1 , 2950 cm -1 and 2850 cm -1 respectively in all the
compounds. Two Carbonyl stretching frequencies were obtained near 1700
cm -1 and 1670 cm -1 in all the compounds while frequency for thioamide group
(>CS) was obtained near 1150 cm -1 in DNJ-1701 to DNJ-1705. Frequencies
for ether linkage, C-N (3°) and C-N (2°) were obtained near 1050 cm -1 , 1350
cm -1 and 1320 cm -1 respectively in all the compounds. Characteristic
frequency for 1, 4-disubstitution (near 820 cm -1 ) was found in DNJ-1602, DNJ-
1604, DNJ-1605, DNJ-1702, DNJ-1704 and DNJ-1705 while for 1, 3disubstitution
(near 770 cm -1 ) was found in DNJ-1603 and DNJ-1703.
Characteristic frequencies for C-Cl (near 870 cm -1 ), C-F (near 990 cm -1 ) were
found in DNJ-1604, DNJ-1704 and DNJ-1605, DNJ-1705 respectively.
4.11.3 1 H NMR SPECTRAL STUDY
1 13
H & C NMR spectra of the synthesized compounds were recorded
on Bruker Avance II 400 spectrometer. Sample solutions were made in
CDCl3 solvent using tetramethylsilane (TMS) as the internal standard unless
otherwise mentioned. Numbers of protons and numbers of carbons identified
from H NMR & C NMR spectrum and their chemical shift (δ ppm) were in the
agreement of the structure of the molecule. J values were calculated to
identify o, m and p coupling. In some cases, aromatic protons were obtained
as multiplet. 1 H & 13 C NMR spectral interpretation can be discussed as under.
1 H NMR spectral interpretation of 3-{[3-(4-chlorophenyl)-1-phenyl-1H-
pyrazol-4-yl] methylene}-1-(2, 6-dichlorophenyl)-1, 3-dihydro-2H-indol-2-
one (DNJ-705)
Department of Chemistry, Saurashtra University, Rajkot – 360 005 242