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Chapter – 1 Preparation and Yield optimization.....
1.6 SPECTRAL DISCUSSION
1.6.1 MASS SPECTRAL STUDY
Mass spectra of the synthesized compounds were recorded on
Shimadzu GC-MS QP-2010 model using direct injection probe technique.
The molecular ion peak was found in agreement with molecular weight of the
respective compound. Characteristic M +2 ion peaks with one-third intensity of
molecular ion peak were observed in case of compounds having chlorine
atom. Fragmentation pattern can be observed to be particular for these
compounds and the characteristic peaks obtained for each compound.
Probable fragmentation pattern for DNJ-102 and DNJ-206 can be discussed
as under.
2-methyl-1-(morpholin-4-ylmethyl) indoline (DNJ-102)
1. The target compound showed characteristic molecular ion peak.
2. C2-C3 and C5-C6 bond cleavage gave characteristic peak at 190 m/e.
[1]
3. C3-N4 and C5-N4 bond cleavage gave characteristic peak at 160 m/e.
[2]
4. N4-C7 bond cleavage gave characteristic peak, which is the BASE
PEAK at 146 m/e. [3]
5. C7-N8 bond cleavage gave two characteristic peaks. One peak at 130
m/e and second peak at 100 m/e , which is the second intense peak in
the spectrum. [4]
6. After cleaved from bond C7-N8, C9-C17 bond cleavage gave
characteristic peak at 118 m/e. [5]
Department of Chemistry, Saurashtra University, Rajkot-360 005 46