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Chapter – 3 Preparation of small library…..<br />

3.2.4 PREPARATION OF 2-AMINO BENZOTHIAZOLE<br />

R<br />

Reagents / Reaction Condition (d): KSCN, Br2, Glacial acetic acid / 0-5°C.<br />

3.2.5 PREPARATION OF 3-((UN) SUBSTITUTED 1, 3-BENZOTHIAZOL-2-<br />

YL IMINO)-1, 3-DIHYDRO-2H-INDOL-2-ONE<br />

R<br />

Reagents / Reaction Condition (e): Isatin, Ethanol, Con. H2SO4 / Reflux, 4<br />

hours.<br />

3.2.6 SCHEME - 1<br />

R 1<br />

N<br />

N<br />

R 2<br />

O<br />

N<br />

S<br />

NH 2<br />

O<br />

NH 2<br />

f<br />

d<br />

e<br />

Department of Chemistry, <strong>Saurashtra</strong> <strong>University</strong>, Rajkot – 360 005 150<br />

R<br />

R 1<br />

N<br />

H<br />

N<br />

N<br />

N<br />

R 2<br />

N<br />

N<br />

O<br />

S<br />

O<br />

N<br />

S<br />

NH<br />

O<br />

NH 2<br />

C 3 H 7<br />

R<br />

C 3 H 7

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