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CHAPTER – 6<br />

BIOLOGICAL EVALUATION OF SELECTED NEWLY<br />

SYNTHESIZED COMPOUNDS<br />

6.1 Antimicrobial activity 327<br />

6.1.1 Minimum Inhibitory Concentration (MIC) 327<br />

6.1.2 Protocol for antibacterial activity 328<br />

6.1.3 Results and discussion 331<br />

6.2 Cytotoxicity assay (anticancer activity) 334<br />

6.2.1 Results and discussion 335<br />

6.3 In silico study for DNJ-701 339<br />

6.3.1 Toxicity risk assessment 340<br />

6.3.2 logS calculation 342<br />

6.3.3 Molecular weight 344<br />

6.3.4 Drug likeness 344<br />

6.3.5 Drug score 346<br />

6.3.6 Conclusion 346

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