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Part – B Studies on isatin derivatives…..
OH
O
O
1
N
N CH 2NRR 1
O
N CH 2NRR 1
I
IV
O H
O
N
NCH
2 NRR 1
1 2 3
4 5
NPh
O
N
CH 2OH
I
O
N
CH 2NRR 1
They 238 further carried out condensation of (1) (R = CH2OH, R 1 = H)
with 4-iodoaniline gave (1) (R = H, R 1 = p-IC6H4) and not the expected product
(1) (R = p-IC6H4NHCH2, R 1 = H). (Fig. B.1.9)
R
N
Joshi et. al. 239 prepared fluorotriazinoindoles (1) (R = 7-F, 8-F; N(R 1 )2
= Et2N, piperidino, pyrrolidino, morpholino) and fluorodiazoindolones (2) (R 2 =
Ph, 4-FC6H4, 4-Me2NC6H4, 4-ClC6H4, 2-furyl, 4-O2NC6H4) from
fluoroindolediones (3) (R = 5-F, 6-F). (Fig. B.1.10)
Department of Chemistry, Saurashtra University, Rajkot-360 005 121
NPh
O
N
II
V
O
O
N CH 2NRR 1
Cl
N O
R II
N O
H III
O
N R 1
2
I
III
Fig. B.1.7
3 Fig. B.1.8
1
Fig. B.1.9