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Chapter – 3 Preparation of small library…..<br />

3.5.2 Physical data of 3-(1, 3-benzothiazol-2-ylimino)-1-(substituted-4-<br />

Code<br />

ylmethyl)-1, 3-dihydro-2H-indol-2-one (DNJ-1401 to DNJ-1405)<br />

Substitution<br />

R1 & R2<br />

MF<br />

MW<br />

(g/m)<br />

MP<br />

(°C)<br />

Department of Chemistry, <strong>Saurashtra</strong> <strong>University</strong>, Rajkot – 360 005 160<br />

Rf<br />

%<br />

Yield<br />

DNJ-1401 Morpholine C20H18N4O2S 378 230-232 0.40 60<br />

DNJ-1402 Piperidine C21H20N4OS 376 210-212 0.43 58<br />

DNJ-1403<br />

DNJ-1404<br />

DNJ-1405<br />

1-Methyl<br />

Piperazine C21H21N5OS 391 196-198 0.45 63<br />

1-Ethyl<br />

Piperazine C22H23N5OS 405 234-236 0.49 65<br />

1-Benzyl<br />

Piperazine C27H25N5OS 467 200-202 0.56 57<br />

Rf value was calculated using solvent system = Hexane : Ethyl Acetate (6<br />

: 4)<br />

R 1<br />

N<br />

N<br />

N<br />

R 2<br />

N<br />

O<br />

S

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