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Chapter – 1 Preparation and Yield optimization.....
1.9 CONCLUSION
In this chapter, along with yield optimization of the 2-methyl indoline,
simple, easy and fast method was adopted first time to prepare new Mannich
bases of 2-methyl indoline using formaldehyde solution and primary and
secondary amine. DEPT-135 experiment has proved the possible mechanistic
path governing this reaction, which is probably hitherto unknown in literature.
Antimicrobial data of the synthesized compounds are reported in Chapter – 6.
Department of Chemistry, Saurashtra University, Rajkot-360 005 59