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Chapter – 6 Biological evaluation of newly.....
likeness score although it wouldn't really qualify for being a drug because of
its high lipophilicity.
6.3.5 Drug Score
The drug score value combines all other predictions into one grand total.
Score from logs 0.045 (logs = -8.046)
Score from moleweight 0.351 (mol. weight = 553.0)
Score from druglikeness 0.0 (drug likeness = -8.587)
No risk of Mutagenicity, Score 1.0
No risk of Tumorigenecity, Score 1.0
No risk of Irritating effects, Score 1.0
No risk of Reproductive effects, Score 1.0
(The drug score combines toxicity risks, drug likeness, logS, molecular weight
in one handy value than may be used to judge the compound's overall
potential to qualify for a drug. This value is calculated by multiplying
contributions of the individual properties.)
6.3.6 Conclusion
With the help of above mention data and other experimental results of
compound, it is clear that this compound has fulfilled most of the requirements
of drug like potential and ready for future work and experiment.
Department of Chemistry, Saurashtra University, Rajkot – 360 005 346