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Chapter – 2 Microwave assisted simple and fast…..
9. N4-C7 bond cleavage in the title compound gave characteristic peak at
172 m/e, which could be the alternative possibility for this fragment.
[11]
10. C7-C8 bond cleavage in the title compound gave two characteristic
peaks at 158 m/e and 100 m/e, which could be the alternative
possibility. [12]
11. C8-C9 bond cleavage in the title compound gave two characteristic
peaks at 146 m/e (BASE PEAK) and 118 m/e, which could be the
alternative possibility. [13]
12. C9-N10 bond cleavage in the title compound gave characteristic peak at
130 m/e, which could be the alternative possibility. [14]
2.6.1.1 FRAGMENTATION PATTERN FOR DNJ-302
172 m/e
O
NH
158 m/e
H3C O
N
100 m/e
+.
18
18 +. 18 +. 18 +.
12
12
12
12
17 13
17 13
17 13
17 13
CH3 11 CH 11
3
CH 11
3
CH 11
3
16 14
19
16 14
19
16 14
19
16 14
N
15 N 15 N 15 N 15 N
[11]
10 [1] 10
[2] [3]
10
10
CH 3
+.
91 m/e
N
CH 3
+.
+.
CH 3
O
[12]
146 m/e
C
H 3
N
118 m/e
6
O 1
5
8
N
4
3
7
9
2
260 m/e
[13] [14]
N
CH 3
+.
+.
CH 3
130 m/e
O
N
130 m/e
N
H
+.
CH 3
17
16
H3C 6
18
15
5
H3C 2
13
14
H3C 8
8
N
4
3
17
18
13
12
16
15
14
11
N
10
CH3 19
CH3 9
8
[7]
CH3 172 m/e
7
+.
158 m/e
7
Department of Chemistry, Saurashtra University, Rajkot – 360 005 89
9
12
11
N
10
9
245 m/e
+.
+.
CH 3
19
[6]
H3C 6
17
16
18
15
5
186 m/e
13
14
N 4
H2N 4
8
229 m/e
7
CH 3
3
8
9
12
11
N
10
7
9
CH 3
19
17
18
13
12
[8] 16
15
14
11
N
10
CH3 19 [9]
146 m/e
+.
CH 3
9
+.
118 m/e
N
H
+.
[5]
223 m/e
17
16
H3C 5
18
15
208 m/e H3C 5
17
16
[10]
[4]
18
15
N 4
13
14
8
7
CH 3
3
8
NH
4
9
12
11
N
10
7
9
12
13
11
14
N
H
10
130 m/e
+.
+.
CH 3
19
CH 3
19
CH 3
19