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Chapter – 2 Microwave assisted simple and fast…..
3°), 1048 (C-O-C); 1 H NMR (400 MHz, CDCl3): δ (ppm) 2.61 (4H, t), 3.95 (4H,
t), 4.47 (2H, s), 6.63 (2H, m), 7.00 (2H, m); MS m/z = 274 (M + ); Anal. Calcd.
for C14H14N2O4: C, 61.31; H, 5.14; N, 10.21. Found: C, 61.35; H, 5.10; N,
10.24.
1-[(4-METHYL PIPERAZIN-1-YL) ACETYL]-1H-INDOLE-2, 3-DIONE (DNJ-
603): IR (KBr, cm -1 ): 3070 (Ar-H), 2945 (–CH3), 2860 (–CH2), 1710 (>CO,
C12), 1678 (>CO, C11), 1655 (>CO, C7), 1600, 1588, 1524, 1450 (Ar-H), 1111
(C-N, Aliphatic, 3°); MS m/z = 287 (M + ); Anal. Calcd. for C15H17N3O3: C,
62.71; H, 5.96; N, 14.63. Found: C, 62.75; H, 5.92; N, 14.60.
1-[(4-ETHYL PIPERAZIN-1-YL) ACETYL]-1H-INDOLE-2, 3-DIONE (DNJ-
604): IR (KBr, cm -1 ): 3064 (Ar-H), 2962 (–CH3), 2860 (–CH2), 1720 (>CO,
C12), 1685 (>CO, C11), 1650 (>CO, C7), 1600, 1570, 1500, 1455 (Ar-H), 1123
(C-N, Aliphatic, 3°); MS m/z = 301 (M + ); Anal. Calcd. for C16H19N3O3: C,
63.77; H, 6.36; N, 13.94. Found: C, 63.80; H, 6.33; N, 13.91.
1-[(4-BENZYL PIPERAZIN-1-YL) ACETYL]-1H-INDOLE-2, 3-DIONE (DNJ-
605): IR (KBr, cm -1 ): 3077 (Ar-H), 2950 (–CH3), 2869 (–CH2), 1715 (>CO,
C12), 1680 (>CO, C11), 1662 (>CO, C7), 1612, 1530, 1466, 1420 (Ar-H), 1122
(C-N, Aliphatic, 3°); MS m/z = 363 (M + ); Anal. Calcd. for C21H21N3O3: C,
69.41; H, 5.82; N, 11.56. Found: C, 69.45; H, 5.85; N, 11.60.
Department of Chemistry, Saurashtra University, Rajkot – 360 005 101