Download (4Mb) - Etheses - Saurashtra University

Chapter – 3 Preparation of small library…..
7. After C21-C22 bond cleavage, N13-C21 bond cleavage gave
characteristic peak at 134 m/e. [6]
8. After N13-C21 bond cleavage, C12-O20 bond cleavage gave
characteristic peak at 119 m/e. [7]
3.6.1.3 FRAGMENTATION PATTERN FOR DNJ-1401
17
18
16
19
278 m/e
15
14
N 10
11
12
N
H
13
2
3.6.2 IR SPECTRAL STUDY
O 22
21
CH 3
23
+. 11
[7]
17
16
15
11 +.
12
N
H
13
O
20
18
19
14
12
N
H
13
IR spectra of the synthesized compounds were recorded on Shimadzu
FT IR 8400 spectrophotometer using Diffused Reflectance Attachment (DRA)
System using Potassium Bromide.
N-H stretching frequency was observed near 3430 cm -1 in case of DNJ-
1301 to DNJ-1305. There are two carbonyl groups present in all the
compounds but due to the same environment, the peaks merged in the region
of 1680 cm -1 . C=N stretching frequency was observed near 1610 cm -1 in all
the compounds. C-N stretching (2° & 3°) frequency was found DNJ-1301 to
Department of Chemistry, Saurashtra University, Rajkot – 360 005 166
17
18
16
19
15
14
O 22
NH
10
11
12
N
13
17
18
16
19
15
14
11
12
N
13
O
20
[5]
17
18
16
19
15
14
11
12
N
13
O
20
[4]
17
18
16
19
15
14
11
12
N
13
146 m/e
[6]
CH3 21
160 m/e
O
22
21
176 m/e
O
22
21
17
18
N 3
O 20
S 1
16
19
4
9
8
N
3
4
9
8
5
7
6
[1] 17
16
15
N
10
11
2
S
1
5
6
7
[2]
18
19
14
12
N
13
O
20
15
14
134 m/e
+.
+.
321 m/e
118 m/e
+.
21
[3]
+.
+.
2
O 20
CH 3
23
O 20
CH 3
23
N 3
S 1
4
5
189 m/e
9
6
134 m/e
8
7
+.