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Chapter – 4 Studies on different types of reactions…..
4.11 SPECTRAL DISCUSSION
4.11.1 MASS SPECTRAL STUDY
Mass spectra of the synthesized compounds were recorded on
Shimadzu GC-MS QP-2010 model using direct injection probe technique.
The molecular ion peak was found in agreement with molecular weight of the
respective compound. Characteristic M +2 ion peaks with one-third intensity of
molecular ion peak were observed in case of compounds having chlorine
atom. Fragmentation pattern can be observed to be particular for these
compounds and the characteristic peaks obtained for each compound.
Probable fragmentation pattern for DNJ-705, DNJ-804, DNJ-905, DNJ-1605
and DNJ-1705 can be discussed as under.
3-{[3-(4-chlorophenyl)-1-phenyl-1H-pyrazol-4-yl] methylene}-1-(2, 6-
dichlorophenyl)-1, 3-dihydro-2H-indol-2-one (DNJ-705)
1. The target compound showed characteristic molecular ion peak.
2. C2-C16 bond cleavage gave characteristic peak at 524 m/e. [1]
3. Loss of one chlorine atom (C28-Cl37 bond cleavage) from title
compound gave characteristic peak at 506 m/e. [2]
4. Loss of two chlorine atoms (C11-Cl23 and C15-Cl24 bond cleavages)
gave characteristic peak at 478 m/e. [3]
5. N21-C31 bond cleavage gave characteristic peak at 464 m/e. (loss of
one phenyl ring) [4]
6. Loss of all the three chlorine atoms, from the title compound gave
characteristic peak at 442 m/e. (C28-Cl37, C11-Cl23 and C15-Cl24 bond
cleavages) [5]
7. C17-C18 bond cleavage gave two characteristic peaks at 290 m/e and
253 m/e respectively. [6]
Department of Chemistry, Saurashtra University, Rajkot – 360 005 235