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Chapter – 2 Microwave assisted simple and fast…..
for C16H22N2O: C, 74.38; H, 8.58; N, 10.84. Found: C, 74.34; H, 8.54; N,
10.80.
2-METHYL-1-(2-MORPHOLIN-4-YL-2-OXO ETHYL) INDOLINE (DNJ-402):
IR (KBr, cm -1 ): 3110 (Ar-H), 2949 (–CH3), 2855 (–CH2), 1735 (>CO), 1613,
1469, 1439 (Ar-H), 1113 (C-N, Aliphatic, 3°), 1050 (C-O-C); 1 H NMR (400
MHz, CDCl3): δ (ppm) 1.28 (3H, m), 2.45 (4H, t), 2.62 (1H, s), 2.83 (1H, s),
3.14 (1H, s), 3.73 (4H, t), 4.44 (2H, s), 6.63 (2H, m), 7.00 (2H, m); MS m/z =
260 (M + ); Anal. Calcd. for C15H20N2O2: C, 69.20; H, 7.74; N, 10.76. Found: C,
69.24; H, 7.70; N, 10.80.
2-METHYL-1-[2-(4-METHYL PIPERAZIN-1-YL)-2-OXO ETHYL] INDOLINE
(DNJ-403): IR (KBr, cm -1 ): 3082 (Ar-H), 2964 (–CH3), 2859 (–CH2), 1730
(>CO), 1627, 1534, 1480, 1423 (Ar-H), 1120 (C-N, Aliphatic, 3°); MS m/z =
273 (M + ); Anal. Calcd. for C16H23N3O: C, 70.30; H, 8.48; N, 15.37. Found: C,
70.26; H, 8.46; N, 15.40.
1-[2-(4-ETHYL PIPERAZIN-1-YL)-2-OXO ETHYL]-2-METHYL INDOLINE
(DNJ-404): IR (KBr, cm -1 ): 3105 (Ar-H), 2969 (–CH3), 2848 (–CH2), 1722
(>CO), 1662, 1500, 1447 (Ar-H), 1110 (C-N, Aliphatic, 3°); MS m/z = 287
(M + ); Anal. Calcd. for C17H25N3O: C, 71.04; H, 8.77; N, 14.62. Found: C,
71.08; H, 8.80; N, 14.65.
1-[2-(4-BENZYL PIPERAZIN-1-YL)-2-OXO ETHYL]-2-METHYL INDOLINE
(DNJ-405): IR (KBr, cm -1 ): 3068 (Ar-H), 2963 (–CH3), 2865 (–CH2), 1730
(>CO), 1620, 1470, 1445 (Ar-H), 1130 (C-N, Aliphatic, 3°); MS m/z = 349
(M + ); Anal. Calcd. for C22H27N3O: C, 75.61; H, 7.79; N, 12.02. Found: C,
75.57; H, 7.82; N, 12.05.
1-(3-PIPERIDIN-1-YL PROPYL)-1H-INDOLE-2, 3-DIONE (DNJ-501): IR
(KBr, cm -1 ): 3100 (Ar-H), 2963 (–CH3), 2846 (–CH2), 1724 (>CO, C12), 1680
(>CO, C11), 1610, 1555, 1448 (Ar-H), 1120 (C-N, Aliphatic, 3°); MS m/z = 272
(M + ); Anal. Calcd. for C16H20N2O2: C, 70.56; H, 7.40; N, 10.29. Found: C,
70.60; H, 7.42; N, 10.32.
Department of Chemistry, Saurashtra University, Rajkot – 360 005 99