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Chapter – 3 Preparation of small library…..<br />

3.5 PHYSICAL DATA TABLES<br />

3.5.1 Physical data of N'-{1-[(substituted-1-yl) methyl]-2-oxo-1, 2-<br />

Code<br />

dihydro-3H-indol-3-ylidene}-2-propylpentanohydrazide (DNJ-1301<br />

to DNJ-1305)<br />

Substitution<br />

R1 & R2<br />

MF<br />

MW<br />

(g/m)<br />

MP<br />

(°C)<br />

Department of Chemistry, <strong>Saurashtra</strong> <strong>University</strong>, Rajkot – 360 005 159<br />

Rf<br />

%<br />

Yield<br />

DNJ-1301 Morpholine C21H30N4O3 386 180-182 0.43 71<br />

DNJ-1302 Piperidine C22H32N4O2 384 176-178 0.41 69<br />

DNJ-1303<br />

DNJ-1304<br />

DNJ-1305<br />

1-Methyl<br />

Piperazine<br />

1-Ethyl<br />

Piperazine<br />

1-Benzyl<br />

Piperazine<br />

C22H33N5O2 399 204-206 0.44 67<br />

C23H35N5O2 413 222-224 0.48 70<br />

C28H37N5O2 475 190-192 0.55 65<br />

Rf value was calculated using solvent system = Toluene : Ethyl Acetate<br />

(7 : 3)<br />

R 1<br />

N<br />

N<br />

N<br />

R 2<br />

O<br />

NH<br />

O<br />

C 3 H 7<br />

C 3 H 7

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