Download (4Mb) - Etheses - Saurashtra University

Chapter – 1 Preparation and Yield optimization.....
1.6.2 IR SPECTRAL STUDY
IR spectra of the synthesized compounds were recorded on Shimadzu
FT-IR 8400 spectrophotometer using Diffused Reflectance Attachment (DRA)
system using Potassium Bromide.
In case of DNJ-101 to DNJ-111, there is no characteristic peak
obtained in the spectra except C-H stretching and bending and ring skeleton
due to the absence of the functional group. In case of DNJ-103 secondary
amine of piperazine gave stretching frequency in the region of 3310 to 3500
cm -1 and bending vibrations in the region of 1550 to 1650 cm -1 . Aliphatic C-N
vibrations are found near 1220 cm -1 . C-O-C ether linkage also showed a
characteristic frequency in DNJ-102.
DNJ-201 to DNJ-210 compounds showed N-H stretching vibrations in
the region of 3310 to 3500 cm -1 DNJ-206 and DNJ-207. Frequency for m di
substitution has been found in DNJ-202 to DNJ-205. DNJ-202 and DNJ-203
showed C-X stretching frequency. C-O-C ether linkage also showed a
characteristic frequency in DNJ-205 and DNJ-210.
1.6.3 1 H & 13 C NMR SPECTRAL STUDY
1 13
H & C NMR (DEPT 135) spectra of the synthesized compounds
were recorded on Bruker Avance II 400 spectrometer. Making a solution of
samples in CDCl3 solvent using tetramethylsilane (TMS) as the internal
standard unless otherwise mentioned. Numbers of protons and carbons
identified from NMR spectrum and their chemical shift (δ ppm) were in the
agreement of the structure of the molecule. J values were calculated to
identify o, m and p coupling. In some cases, aromatic protons were obtained
as multiplet. 1 H & 13 C NMR (DEPT 135) spectral interpretation can be
discussed as under.
Department of Chemistry, Saurashtra University, Rajkot-360 005 49