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Chapter – 1 Preparation and Yield optimization.....
4. N11-C14 bond cleavage gave characteristic peak at 177 m/e. [3]
5. Cleavage of the bonds between N11-C12 and N11-C14 gave
6.
characteristic peak at 160 m/e. [4]
N11-C10 bond cleavage gave two characteristic peaks. One peak at 146
m/e which is the BASE PEAK and second peak at 106 m/e. [5]
7. N1-C10 bond cleavage gave two characteristic peaks. One peak at 130
m/e and second peak at 120 m/e which is the second intense peak in
the spectrum. [6]
1.6.1.2 FRAGMENTATION PATTERN FOR DNJ-206
C
H 3
NH
177 m/e
N
C
H 3
N
CH 3
N
190 m/e
CH 3
N
H 2
+ .
N
160 m/e
CH 3
[3]
CH 3
+ .
[2]
C
H 3
C
H 2
7
8
6
H3C 12
N
9
5
N 11
Department of Chemistry, Saurashtra University, Rajkot-360 005 48
4
N
216 m/e
[1]
CH 3
N
1
10
3
2
CH 3
CH 3
13
14
[4] 15 19
N
+
.
H
16 18
3C
CH3 NH
+ 17
.
252 m/e
[6]
+ .
[5]
130 m/e
C
H 3
N
120 m/e
N
H
CH 3
+ .
106 m/e
CH 3
+ .
CH 3
146 m/e
+ .