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Chapter – 3 Preparation of small library…..
3.7 ANALYTICAL DATA
N'-[1-(MORPHOLIN-4-YL METHYL)-2-OXO-1, 2-DIHYDRO-3H-INDOL-3-
YLIDENE]-2-PROPYLPENTANOHYDRAZIDE (DNJ-1301): IR (KBr, cm -1 ):
3432 (-NH), 2955 (-CH3), 2862 (-CH2), 1680 (>CO), 1610 (-C=N), 1458 (Ar-H,
ben), 1311 (C-N, Ar, 2°), 1213 (C-N, Aliphatic, 3°), 1050 (C-O-C); 1 H NMR
(400 MHz, CDCl3): δ (ppm) 1.37 (6H, t), 1.53 (4H, qt), 1.79 (4H, m), 2.90 (4H,
m), 3.69 (4H, q), 4.48 (2H, s), 7.15 (1H, q, J = 7.92 Hz), 7.39 (1H, qt), 7.62
(1H, d, J = 7.28 Hz), 7.80 (1H, d, J = 7.36 Hz), 12.52 (1H, s); 13 C NMR (400
MHz, CDCl3): δ (ppm) 179.30, 173.69, 161.61, 143.19, 136.04, 120.33,
119.95, 119.53, 110.44, 66.92, 66.59, 51.94, 51.00, 34.58, 20.68, 14.07; MS
m/z = 386 (M + ); Anal. Calcd. for C21H30N4O3: C, 65.26; H, 7.82; N, 14.50.
Found: C, 65.21; H, 7.85; N, 14.47.
N'-[2-OXO-1-(PIPERIDIN-1-YL METHYL)-1, 2-DIHYDRO-3H-INDOL-3-
YLIDENE]-2-PROPYLPENTANOHYDRAZIDE (DNJ-1302): IR (KBr, cm -1 ):
3430 (-NH), 2957 (-CH3), 2859 (-CH2), 1682 (>CO), 1608 (-C=N), 1460 (Ar-H,
ben), 1309 (C-N, Ar, 2°), 1210 (C-N, Aliphatic, 3°), 1055 (C-O-C); MS m/z =
384 (M + ); Anal. Calcd. for C22H32N4O2: C, 68.72; H, 8.39; N, 14.57. Found: C,
68.76; H, 8.43; N, 14.53.
N'-{1-[(4-METHYL PIPERAZIN-1-YL) METHYL]-2-OXO-1, 2-DIHYDRO-3H-
INDOL-3-YLIDENE}-2-PROPYLPENTANOHYDRAZIDE (DNJ-1303): IR
(KBr, cm -1 ): 3428 (-NH), 2962 (-CH3), 2854 (-CH2), 1679 (>CO), 1605 (-C=N),
1464 (Ar-H, ben), 1311 (C-N, Ar, 2°), 1214 (C-N, Aliphatic, 3°), 1053 (C-O-C);
MS m/z = 399 (M + ); Anal. Calcd. for C22H33N5O2: C, 66.14; H, 8.33; N, 17.53.
Found: C, 66.10; H, 8.37; N, 17.50.
N'-{1-[(4-ETHYL PIPERAZIN-1-YL) METHYL]-2-OXO-1, 2-DIHYDRO-3H-
INDOL-3-YLIDENE}-2-PROPYLPENTANOHYDRAZIDE (DNJ-1304): IR
(KBr, cm -1 ): 3431 (-NH), 2960 (-CH3), 2856 (-CH2), 1682 (>CO), 1607 (-C=N),
1462 (Ar-H, ben), 1310 (C-N, Ar, 2°), 1212 (C-N, Aliphatic, 3°), 1051 (C-O-C);
Department of Chemistry, Saurashtra University, Rajkot – 360 005 172