Chapter – 4 Studies on different types of reactions….. 234 D. Hadlipavlou-Litina; J. Arzneim-Forsch./Drug Res., 2000, 50, 631. 235 M. Ferrer, J. Leiton and L. Zaton; J. Protein Chem., 1998, 17, 115. 236 G. Roma, M. Di Braccio, A. Carrieri, G. Grossi, G. Leoncini, G. Signorello and A. Carotti; Bioorg. & Med. Chem., 2003, 11, 123. 237 F. Chiou, L. Huang, F. Chen and C. Chen; Planta Med., 2001, 67, 282. 238 R. Pignatello, A. Puleo, S. Giustolisi, S. Cuzzoccrea, L. Dugo, P. Caputi and G. Puglisi; Drug Dev. Res., 2002, 57, 115. 239 L. Santana, E. Uriarte, Y. Fall, M. Teijeira, C. Teran, E. Garcia-Martinez and R. Tolf; Eur. J. Med. Chem., 2002, 37, 503. 240 M. Gonzalez-Gomez, L. Santana, E. Uriarte, J. Brea, M. Villlazon, I. Loza, M. De Luca, E. Rivas, Y. Montegero and A. Fontela; Bioorg. & Med. Chem. Lett., 2003, 13, 175. 241 V. Kostanecki and J. Tambor; Ber., 1921, 32, 1899. 242 A. G. Perkin and H. Jummel; J. Chem. Soc., 1904, 1461. 243 A. Goschke and J. Tambor; Ber., 1911, 44, 3502. 244 J. Shinoda, S. Sato and M. Kawagoe; J. Pharm. Soc. Japan., 1929, 49, 548. 245 R. Robinson; CA 24:604. 246 R. Segesser and M. Calvin; J. Am. Chem. Soc., 1942, 64, 825. 247 O. Tunman; Pharm. Post., 1917, 90, 773. 248 H. Sakanaki and N. Todd: CA 12:1344. 249 E. E. Kleider and E. E. Swanson; J. Am. Chem. Soc., 1929, 51, 1267. 250 F. E. King, T. J. King and K. G. Neill; J. Chem. Soc., 1954, 1055. (CA 48:58333g) 251 M. kametaka and A. G. Perkin; J. Chem. Soc., 1990, 1415 252 W. B. Geiger and J. E. Conn; J. Am. Chem. Soc., 1945, 67, 112. 253 D. H. Marian, P. B. Russel and A. R. Todd; J. Chem. Soc., 1947, 1419. 254 D. N. Dhar; “Chemistry of Chalcone”, Wiley, New York, 1981. 255 B. Prescott; Int. J. Clin., Pharmacol. Bio. Pharm., 1975, 11(4), 332. (CA 83:126292d) 256 D. Binder, C. R. Noc W. Holzer and B. Roscnwirth; Arch. Pharma., 1989, 318(1), 48. (CA 102:149025) 257 J. C. Dore and C. Viel; J. Pharma. Belg., 1974, 29(4), 341. (CA 83:90650c) 258 S. Matsunaka; J. Agri. Food Chem., 1969, 17, 191. 259 G. Devaux, A. Nuhrich, V. Dargelos and M. Capdepay; Fr. Demande, 1978, 2, 357. 260 O. Sullivan; CA 89:163384e. 261 S. S. Sardjiman, M. S. Reksohadiprodjo, L. Hakim and H. Timmerman; Eur. J. Med. Chem., 1997, 32, 625. 262 J. Milobeddzka, S. Kostanecki and V. Lampe; Chem. Ber., 1910, 43, 2163. 263 R. C. Shrimal and B. N. Dhawan; J. Pharma. Pharmacol., 1972, 25, 447. 264 A. Mukhopadhyay, N. Basu and P.K. Gujar; Agent Actions, 1982, 12, 508. 265 O. P. Sharma; Biochem. Pharmacol., 1972, 25, 1811. Department of Chemistry, <strong>Saurashtra</strong> <strong>University</strong>, Rajkot – 360 005 273
Chapter – 4 Studies on different types of reactions….. 266 T. Kosuge, H. Ishida and H. Yamazaka; Chem. Pharma. Bull. (Tokyo), 1985, 33, 1499. 267 H. H. Tonnesen; Inst. J. Pharma., 1989, 50, 67. 268 E. Kunchandy and M. N. A. Rao; Inst. J. Pharma., 1990, 58, 237. 269 S. C. Sharma, H. Mukhtar, S. K. Sharma and M. Krishna; Biochem. Pharmacol., 1972, 21, 1210. 270 A. N. Nurfina, M. S. Rekehhdiprojo, H. Timmerman, U. A. Jenie, D. Sugiyanto and V. Goot; Eur. J. Med. Chem., 1997, 32, 321. 271 V. V. Mulwad and R. D. Bhagat; Ind. J. Het. Chem., 1999, 9(1), 13. 272 D. Zavrsnik, F. Basic, F. Becic, E. Becic and S. Jazic; Periodicum Biologorum, 2003, 105(2), 137. 273 M. S. Mohamed, W. A. Zaghary, T. S. Hafez, N. M. Ibrahim, M. M. Abo El-Alamin and M. R. H. Mahran; Bull. Facul. Pharm., 2002, 40(1), 175. 274 G.-H. Ding, S.-P. Jing and H. Tian; Yingyong Huaxue, 2005, 22(5), 551. 275 V. M. Kulkarni, V. Hariprasad and T. T. Talele; Indian Pat. Appl. IN 1996BO00366, 2005. 276 S. Jang, J.-C. Jung and S. Oh; Bioorg. & Med. Chem., 2007, 15(12), 4098. 277 J. C. Trivedi, J. B. Bariwal, K. D. Upadhyay, Y. T. Naliapara, S. K. Joshi, C. C. Pannecouque, E. De Clercq and A. K. Shah; Tet. Lett., 2007, 48(48), 8472. 278 J. Kolsa; Arch. Pharm., 1953, 286, 37. (CA 48:12093) 279 G. P. Ellis; Heterocyclic Compounds, J.W.; Interscience, 1977, 430. 280 M. Eckstein and J. Sulko; Annali di Chimica (Rome, Italy, 1965, 55(4), 365. 281 M. Eckstein, A. Koewa and H. Pazdro; Roczniki Chemii., 1958, 32, 789. 282 M. Eckstein, A. Koewa and H. Pazdro; Roczniki Chemii., 1958, 32, 801. 283 W. R. Sullivan, C. F. Huebner, M. A. Stahmann and K. P. Link; J. Am. Chem. Soc., 1943, 65, 2288. 284 A. Koewa, M. Eckstein and H. Pazdro; Dissertationes Pharmaceuticae., 1959, 11, 243. 285 J. Riboulleau, C. Deschamps-Vallet, D. Molho and C. Mentzer; Bulletin de la Societe Chimique de France Bull Soc Chim Fr., 1970, 8-9, 3138. 286 M. Covello, E. Abignente and A. Manna; Rendiconto dell’Accademia delle Scienze Fisiche e Matematiche, Naples., 1971, 38, 259. 287 M. Ikawa, M. A. Stahmann and K. P. Link; J. Am. Chem. Soc., 1944, 66, 902. 288 G. Casini, F. Gaultieri and M.L. Stein; J. Het. Chem., 1965, 2(4), 385. 289 K. Fucik, J. F. Koristek and B. Kakac; Colle. Czechoslovak Chem. Commun., 1952, 46, 148. (CA 47:8740) 290 S. F. Z. Spofa and P. Narodni; Austrian Patent 177 416, 1954. 291 K. Fucik and S. Koristek; Czech Patent 84, 851, 1955. 292 K. Fucik; German (East) Patent 11, 295, 1956. Department of Chemistry, <strong>Saurashtra</strong> <strong>University</strong>, Rajkot – 360 005 274
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Saurashtra University Re - Accredit
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Statement under O. Ph. D. 7 of Saur
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ACKNOWLEDGEMENT It is a moment of g
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Jignesh Lunagariya, Hitesh Sarvaiya
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CONTENT Content General Remarks 6 A
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Content 3.2 Reaction scheme 149 3.3
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5.14 Conclusion 313 5.15 Spectral r
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MF Molecular Formula MW Molecular W
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GABA Gamma Amino Butyric Acid MES M
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PART - A STUDIES ON 2-METHYL INDOLI
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Part-A Studies on 2-methyl indoline
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Conferences / Seminar / Workshop At