Mayo Test Catalog, (Sorted By Test Name) - Mayo Medical ...

FICEP
91172
levels of imipramine and desipramine are between 175 and 300 ng/mL. Risk of toxicity is increased
with levels > or =300 ng/mL. Most individuals display optimal response to desipramine with serum
levels of 100 to 300 ng/mL. Risk of toxicity is increased with desipramine levels > or =300 ng/mL.
Some individuals may respond well outside of these ranges, or may display toxicity within the
therapeutic range, thus interpretation should include clinical evaluation. Therapeutic ranges are based on
specimen drawn at trough (ie, immediately before the next dose).
Reference Values:
IMIPRAMINE AND DESIPRAMINE
Total therapeutic concentration: 175-300 ng/mL
Total toxic concentration: > or =300 ng/mL
DESIPRAMINE ONLY
Therapeutic concentration: 100-300 ng/mL
Toxic concentration: > or =300 ng/mL
Note: Therapeutic ranges are for specimens drawn at trough (ie, immediately before next scheduled
dose). Levels may be elevated in non-trough specimens.
Clinical References: 1. Wille SM, Cooreman SG, Neels HM, Lambert WE: Relevant issues in the
monitoring and the toxicology of antidepressants. Crit Rev Clin Lab Sci 2008;45(1):25-89 2. Thanacoody
HK, Thomas SH: Antidepressant poisoning. Clin Med 2003;3(2):114-118 3. Baumann P, Hiemke C,
Ulrich S, et al: The AGNP-TDM expert group consensus guidelines: therapeutic drug monitoring in
psychiatry. Pharmacopsychiatry 2004;37(6):243-265
Immune Complex Expanded Panel
Reference Values:
PEG IgG
REFERENCE RANGE: < 3.5 mg/dL
INTERPRETIVE CRITERIA:
< 3.5 mg/dL Normal level
> or = 3.5 mg/dL Elevated level
The PEG method is both antigen and antibody non-specific
and is based on the property of immune complexes to
precipitate at low concentrations of PEG (2.5-3.5%). The
PEG method will precipitate immune complexes of various
sizes and composition as well as other macromolecules
present in serum. Elevated serum IgG may cause a false
positive increase in the PEG precipitate.
Test Performed by: Focus Diagnostics, Inc
5785 Corporate Avenue
Cypress, CA 90630-4750
Immune Complex, C1q
REFERENCE RANGE: < or = 25.1 mcg Eq/mL
Test Performed by: Quest Diagnostics Nichols Institute
33608 Ortega Highway
San Juan Capistrano, CA 92690-6130
C3d Immune Complex
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