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Mayo Test Catalog, (Sorted By Test Name) - Mayo Medical ...

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17-Hydroxyprogesterone, Serum - DHEA_/81405 Dehydroepiandrosterone (DHEA), Serum -<br />

ANST/9709 Androstenedione, Serum Cortisol should be measured in all cases of suspected CAH.<br />

Useful For: Diagnosis of suspected 11-hydroxylase deficiency, including the differential diagnosis of<br />

11 beta-hydroxylase 1 (CYP11B1) versus 11 beta-hydroxylase 2 (CYP11B2) deficiency, and the<br />

diagnosis of glucocorticoid-responsive hyperaldosteronism. This test should be used in conjunction with<br />

measurements of 11-deoxycortisol, 11-corticosteone, 18-hydroxycorticosterone, cortisol, renin, and<br />

aldosterone. Evaluating congenital adrenal hyperplasia newborn screen-positive children, when elevations<br />

of 17-hydroxyprogesterone are only moderate, thereby suggesting possible 11-hydroxylase deficiency.<br />

This test should be used in conjunction with 11-deoxycortisol and 11-deoxycorticosteorone measurements<br />

as an adjunct to 17-hydroxyprogesterone, aldosterone and cortisol measurements.<br />

Interpretation: In 11 beta-hydroxylase 1 (CYP11B1) deficiency, serum concentrations of cortisol will<br />

be low (usually

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