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Mayo Test Catalog, (Sorted By Test Name) - Mayo Medical ...

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FAPG<br />

91347<br />

FADMK<br />

91925<br />

RACTH<br />

82140<br />

33608 ORTEGA HIGHWAY<br />

SAN JUAN CAPISTRANO, CA 92690-6130<br />

ADmark ApoE Genotype Analysis & Interpretation<br />

(Symptomatic)<br />

Reference Values:<br />

A final report will be faxed under separate cover.<br />

TEST PERFORMED BY ATHENA DIAGNOSTICS<br />

377 PLANTATION ST<br />

FOUR BIOTECH PARK<br />

WORCESTER, MA 01605<br />

Clinical References: Corder EH, et al. Science 1993; 261:921-923 Athena Diagnostics, Inc., ApoE<br />

Reported Results, Data on file Welsh-Bohmer, et al. Annals of Neurology 1997; 42:319-325 Saunders,<br />

AM et al. Lancet 1996; 348:90-93 Motter R, et al. Annals of Neurology 1995; 38:643-47 Tanzi R, et al.<br />

Lancet 1996; 347:1091-1095<br />

ADmark Phospho-Tau/Total-Tau/Ab42 CSF Analysis &<br />

Interpretation (Symptomatic)<br />

Reference Values:<br />

A final report will be faxed under separate cover.<br />

<strong>Test</strong> Performed by: Athena Diagnostics<br />

377 Plantation St.<br />

Four Biotech Park<br />

Worcester, MA 01605<br />

Adrenocorticotrophic Hormone, ACTH, IgE<br />

Clinical Information: Clinical manifestations of immediate hypersensitivity (allergic) diseases are<br />

caused by the release of proinflammatory mediators (histamine, leukotrienes, and prostaglandins) from<br />

immunoglobulin E (IgE)-sensitized effector cells (mast cells and basophils) when cell-bound IgE<br />

antibodies interact with allergen. In vitro serum testing for IgE antibodies provides an indication of the<br />

immune response to allergen(s) that may be associated with allergic disease. The allergens chosen for<br />

testing often depend upon the age of the patient, history of allergen exposure, season of the year, and<br />

clinical manifestations. In individuals predisposed to develop allergic disease(s), the sequence of<br />

sensitization and clinical manifestations proceed as follows: eczema and respiratory disease (rhinitis and<br />

bronchospasm) in infants and children less than 5 years due to food sensitivity (milk, egg, soy, and wheat<br />

proteins) followed by respiratory disease (rhinitis and asthma) in older children and adults due to<br />

sensitivity to inhalant allergens (dust mite, mold, and pollen inhalants).<br />

Useful For: <strong>Test</strong>ing for IgE antibodies may be useful to establish the diagnosis of an allergic disease<br />

and to define the allergens responsible for eliciting signs and symptoms. <strong>Test</strong>ing also may be useful to<br />

identify allergens which may be responsible for allergic disease and/or anaphylactic episode, to confirm<br />

sensitization to particular allergens prior to beginning immunotherapy, and to investigate the specificity of<br />

allergic reactions to insect venom allergens, drugs, or chemical allergens.<br />

Interpretation: Detection of IgE antibodies in serum (Class 1 or greater) indicates an increased<br />

likelihood of allergic disease as opposed to other etiologies and defines the allergens that may be<br />

responsible for eliciting signs and symptoms. The level of IgE antibodies in serum varies directly with the<br />

concentration of IgE antibodies expressed as a class score or kU/L.<br />

Current as of January 3, 2013 2:22 pm CST 800-533-1710 or 507-266-5700 or <strong>Mayo</strong><strong>Medical</strong>Laboratories.com Page 60

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