Mayo Test Catalog, (Sorted By Test Name) - Mayo Medical ...

FCLOZ
57284
FCLOM
57276
CLONS
500108
Hematol Educ Program 2009;421-429 4.Sayala HA, Rawstron AC, Hillmen P: Minimal residual disease
assessment in chronic lymphocytic leukaemia. Best Pract Res Clin Haematol 2007;20:499-512
5.Rawstron AC, Villamor N, Ritgen M, et al: International standardized approach for flow cytometric
residual disease monitoring in chronic lymphocytic leukaemia. Leukemia 2007;21:956-964 6.Moreton
P, Kennedy B, Lucas G, et al: Eradication of minimal residual disease in B-cell chronic lymphocytic
leukemia after alemtuzumab therapy is associated with prolonged survival. J Clin Oncol
2005;23:2971-2979
Clobazam, Serum/Plasma
Reference Values:
Reporting limit determined each analysis
Following a single 20 mg oral dose, the mean peak plasma concentration: 465 ng/mL
(range, 220 - 710 ng/mL) after 1.7 hours.
Following a single 40 mg oral dose, the mean peak plasma concentration: 730 ng/mL at 2.5 hours.
The plasma concentration decreased to 360 ng/mL at 12 hours, 180 ng/mL at 48 hours and 17 ng/mL at
96 hours.
Test Performed by: NMS Labs
3701 Welsh Road
P.O. Box 433A
Willow Grove, PA 19090-0437
Clomipramine (Anafranil) and Desmethylclomipramine
Reference Values:
Clomipramine 70 - 200 ng/mL
Desmethylclomipramine 150 - 300 ng/mL
Desired clomipramine concentrations for the treatment of chronic pain: 20 - 85 ng/mL
Test Performed by: Medtox Laboratories, Inc.
402 W. County Road D
St. Paul, MN 55112
Clonazepam, Serum
Clinical Information: Clonazepam is benzodiazepine derivative that is useful alone or as an adjunct
in the treatment of the Lennix-Gastaut syndrome (petit mal variant), akinetic and myoclonic seizures.
Clonazepam has been shown to be effective in patients with absence seizures (petit mal) who have failed
to respond to succinimide therapy. In some studies, up to 30% of patients have shown a loss of
anticonvulsant activity, often within 3 months of administration. In some cases, dosage adjustment may
reestablish efficiency.
Useful For: Clonazepam is a long-acting benzodiazepine restricted in use to those patients who have
responded for seizure control only to diazepam, but who no longer respond to diazepam within non-toxic
levels. It is an effective anticonvulsant, but used only as a last resort due to its side effects.
Reference Values:
Therapeutic concentration: 20-60 ng/mL
Toxic concentration: >100 ng/mL
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