Mayo Test Catalog, (Sorted By Test Name) - Mayo Medical ...

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88501
Interpretation: A written report is issued upon completion of immunohistologic examination. If
material is also submitted for light microscopy, the immunohistologic report will be incorporated with
the light microscopic findings and a written report will be issued.
Reference Values:
An interpretive report will be provided.
Clinical References: Velosa JA, Holley KE: Pathology and immunopathology of renal diseases. In
Renal Function Tests: Clinical Laboratory Procedures and Disorders. Edited by CG Duarte. Boston,
MA, Little, Brown, and Company, 1980, pp 347-385
Renal Biopsy, Light Microscopy
Clinical Information: Kidney biopsy has proven to be of value in the clinical evaluation and
management of patients with undiagnosed kidney disease. The clinical setting may include acute renal
failure, nephrotic syndrome, asymptomatic proteinuria and hematuria. Kidney diseases in the setting of
a systemic disease are often diagnosed on kidney biopsy. Biopsy of the transplanted kidney is important
in the determination of the presence of acute rejection, infection, or recurrent disease. Optimal
interpretation of a kidney biopsy requires integration of clinical and laboratory results with light
microscopic, immunofluorescent histology, and electron microscopy findings. Tissue should always be
submitted for evaluation by light microscopy. In some instances, electron microscopy is required (eg,
Alport's syndrome, dense deposit disease, minimal change nephropathy, thin basement membrane
disease, etc.) to make an accurate diagnosis and submission of tissue for immunofluorescent histology is
required to evaluate for immune complex mediated disease. We recommend that additional material be
submitted for evaluation by immunohistologic method.
Useful For: The evaluation of patients with undiagnosed kidney disease Following the progression of
disease or response to therapy Determining the cause of dysfunction in the transplanted kidney
(allograft)
Interpretation: A verbal report is given by phone upon completion of the light microscopic
examination. A written report is subsequently issued along with histologic slides, and will incorporate
results of immunfluorescent histology and/or electron microscopy if performed.
Reference Values:
An interpretive report will be provided.
Clinical References: 1. Tisher CC: Clinical indication for kidney biopsy. In Renal Pathology: with
Clinical and Functional Correlations. Vol. II. 2nd edition. Edited by CC Tisher, BM Brenner.
Philadelphia, JB Lippincott Company, 1993, pp 75-84 2. Pirani CL: Evaluation of kidney biopsy
specimens. In Renal Pathology: with Clinical and Functional Correlations. Vol. II. 2nd edition. Edited
by CC Tisher, BM Brenner. Philadelphia, JB Lippincott Company, 1993, pp 85-115 3. Pirani CL,
Croker BP: Handling and processing of renal biopsy and nephrectomy specimens. In Renal Pathology:
with Clinical and Functional Correlations. Vol. II. 2nd edition. Edited by CC Tisher, BM Brenner.
Philadelphia, JB Lippincott Company, 1993, pp 1683-1694
Renal Pathology Consultation
Clinical Information: The Mayo Renal Pathology service is staffed by board certified pathologists
who have a special interest in non-neoplastic diseases of the kidney. Kidney biopsy has proven to be of
value in the clinical evaluation and management of patients with kidney disease, including acute and/or
chronic renal insufficiency, nephrotic syndrome, nephritic syndrome, proteinuria and/or hematuria, and
in the overall management of renal transplant recipients. Optimal interpretation of a kidney biopsy
requires integration of clinical and laboratory results with light microscopic, immunofluorescent
histology, and electron microscopy findings.
Useful For: The evaluation and management of patients with kidney disease Following the
progression of known renal disease and/or response to therapy Determining the cause of dysfunction in
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