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Mayo Test Catalog, (Sorted By Test Name) - Mayo Medical ...

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FNAD<br />

80761<br />

FNALO<br />

91784<br />

NARC<br />

82026<br />

Nadolol, Serum/Plasma<br />

Reference Values:<br />

Reporting limit determined each analysis<br />

Synonym(s): Corgard<br />

Mean steady-state plasma levels following a daily regimen:<br />

80 mg: 26 - 36 ng/mL<br />

160 mg: 52 - 74 ng/mL<br />

320 mg: 154 - 191 ng/mL<br />

<strong>Test</strong> Performed <strong>By</strong>: NMS Labs<br />

3701 Welsh Road<br />

PO Box 433A<br />

Willow Grove, PA 19090-0437<br />

Naloxone Screen, Total (Conjugated/Unconjugated), Urine<br />

Reference Values:<br />

Reporting limit determined each analysis (screen and confirmation)<br />

Naloxone – Total ng/mL<br />

Synonym(s): Narcan<br />

Naloxone – Confirmation ng/mL<br />

Synonym(s): Narcan<br />

<strong>Test</strong> Performed <strong>By</strong>: NMS Labs<br />

3701 Welsh Road<br />

P.O. Box 433A<br />

Willow Grove, PA 19090-0437<br />

Narcolepsy-Associated Antigen, HLA-DQB1 Typing, Blood<br />

Clinical Information: Narcolepsy is a neurological condition affecting about 0.02% to 0.16% of<br />

African American, Caucasian, and Japanese individuals. It can be quite disabling because it is<br />

characterized by abnormal rapid eye movement (REM) sleep, cataplexy, hypnagogic hallucinations, and<br />

sleep paralysis. Studies have identified DQB1*06:02 as a useful marker of narcolepsy. While<br />

DQB1*06:02 is found in virtually all African American, Caucasian, and Japanese narcoleptics, it must be<br />

clearly understood that some patients do not have this allele and, more importantly, about 25% of normal<br />

people have this gene. Because DQB1*06:02 is present in the normal population, no test for an HLA gene<br />

constitutes a test for narcolepsy. A more reliable approach would be to consider that, in an appropriate<br />

patient, the absence of the strongly associated DQB1*06:02, provides good evidence that the patient does<br />

not have narcolepsy.<br />

Useful For: Ruling out a diagnosis of narcolepsy<br />

Interpretation: If DQB1*06:02 is not detected, the narcolepsy-associated antigen test result will be<br />

reported as negative for DQB1*06:02. If the allele is detected, the result will be reported as positive for<br />

DQB1*06:02.<br />

Reference Values:<br />

Current as of January 3, 2013 2:22 pm CST 800-533-1710 or 507-266-5700 or <strong>Mayo</strong><strong>Medical</strong>Laboratories.com Page 1290

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