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Mayo Test Catalog, (Sorted By Test Name) - Mayo Medical ...

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psittacosis, a disease characterized by pneumonia, headache, altered mentation, and<br />

hepatosplenomegaly. Psittacosis is acquired by airborne transmission from infected birds.<br />

Chlamydophila pneumoniae (formerly known as TWAR and, more recently, as Chlamydia pneumoniae)<br />

causes pneumonia in humans. It is unique because it is a primary pathogen of humans, is spread from<br />

human to human, and apparently has no animal or bird host. Chlamydophila pneumoniae is responsible<br />

for approximately 10% of pneumonia cases. Chlamydia trachomatis has been implicated in a wide<br />

variety of infections in humans. It is a common cause of nongonococcal urethritis and cervicitis, and<br />

many systemic complications of chlamydial infections have been described. In females, this organism is<br />

a cause of pelvic inflammatory disease, salpingitis, and endometritis. In males, epididymitis and Reiter's<br />

syndrome occur. Lymphogranuloma venereum is a sexually transmitted infection caused by Chlamydia<br />

trachomatis. It presents with a transient primary genital lesion followed by suppurative regional<br />

lymphadenopathy. Occasionally, severe proctitis or proctocolitis may develop. Chlamydia trachomatis<br />

also causes ophthalmologic infections, such as trachoma (rare in the United States), adult inclusion<br />

conjunctivitis and inclusion conjunctivitis in neonates. These disorders have traditionally been<br />

diagnosed by cytologic detection or culture. However, molecular detection methods (#81096<br />

"Chlamydia trachomatis by Nucleic Acid Amplification") may now represent a more sensitive<br />

diagnostic approach. Fitz-Hugh and Curtis syndrome (perihepatitis) has been associated with<br />

chlamydiae.<br />

Useful For: As an aid in the clinical diagnosis of chlamydial infections<br />

Interpretation: IgG Chlamydophila pneumoniae > or =1:512 IgG endpoint titers of > or =1:512 are<br />

considered presumptive evidence of current infection. or =1:64 A single specimen endpoint<br />

titer of > or =1:64 and or =1:512 or a 4-fold increase over that of the initial specimen,<br />

current (acute) infection is indicated. Unchanging titers >1:64 and

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