Mayo Test Catalog, (Sorted By Test Name) - Mayo Medical ...

PARVP
86337
PFRUT
82355
testing.
Useful For: Diagnosing erythrovirus B19 (parvovirus) infection
Interpretation: The presence of erythrovirus B19 DNA by PCR indicates infection with this virus.
The absence of erythrovirus B19 DNA by PCR indicates the lack of infection with this virus (see
Cautions).
Reference Values:
Negative
Clinical References: 1. Heegaard ED, Brown KE: Human parvovirus B19. Clin Microbiol Ref
2002;15:485-505 2. Bultmann BD, Klingel K, Soltar K, et al: Fatal parvovirus B19 associated
myocarditis clinically mimicking ischemic heart disease: an endothelial cell-mediated disease. Hum
Pathol 2003;34:92-95 3. Rerolle JP, Helal I, Morelon E: Parvovirus B19 infection after renal
transplantation. Nephrologie 2003;24:309-315 4. Chisaka H, Morita E, Yaegashi N: Parvovirus B19 and
the pathogenesis of anaemia. Rev Med Virol 2003;16:347-359 5. Goto H, Ishida A, Fujii H, et al:
Successful bone marrow transplantation for severe aplastic anemia in a patient with persistent human
parvovirus B19 infection. Int J Hematol 2004;79(4):384-386
Parvovirus B19, Molecular Detection, PCR, Plasma
Clinical Information: B19, previously classified as a parvovirus, is now in the genus erythrovirus
based on preferential replication of this virus in erythroid progenitor cells.(1) Infection with B19 occurs
early in life and the virus is transmitted by respiratory secretion and occasionally by blood products.
Antibody prevalence ranges from 2% to 15% in early adults.(1) B19 may result in an asymptomatic
infection or produce a wide spectrum of disease ranging from erythema infections (slapped cheek
syndrome or fifth disease) in children to arthropathy, severe anemia, and systemic manifestations
involving the central nervous system, heart, and liver depending on the immune competence of the host.
(2,3) Infection with B19 in pregnant women may cause hydrops fetalis, congenital anemia, abortion, or
stillbirth of the fetus.(4) B19 is also the causative agent of persistent anemia usually, but not
exclusively, in immunocompromised patients, transplant patients, and infants. The deficiencies of
appropriate immune responses to B19 impair viral elimination in virus, which results in enlargement of
B19-infected erythroid-lineage cells.(5,6) Most acute infections with B19 are diagnosed in the
laboratory by serologically detecting IgG and IgM class antibodies with enzyme-linked immunosorbent
assay testing.
Useful For: Diagnosing erythrovirus B19 (parvovirus) infection
Interpretation: The presence of erythrovirus B19 DNA by PCR indicates infection with this virus.
The absence of erythrovirus B19 DNA by PCR indicates the lack of infection with this virus (see
Cautions).
Reference Values:
Not applicable
Clinical References: 1. Heegaard ED, Brown KE: Human parvovirus B19. Clin Microbiol Ref
2002;15:485-505 2. Bultmann BD, Klingel K, Soltar K, et al: Fatal parvovirus B19 associated
myocarditis clinically mimicking ischemic heart disease: an endothelial cell-mediated disease. Hum
Pathol 2003;34:92-95 3. Rerolle JP, Helal I, Morelon E: Parvovirus B19 infection after renal
transplantation. Nephrologie 2003;24:309-315 4. Chisaka H, Morita E, Yaegashi N: Parvovirus B19 and
the pathogenesis of anaemia. Rev Med Virol 2003;16:347-359 5. Goto H, Ishida A, Fujii H, et al:
Successful bone marrow transplantation for severe aplastic anemia in a patient with persistent human
parvovirus B19 infection. Int J Hematol 2004;79(4):384-386
Passion Fruit, IgE
Clinical Information: Clinical manifestations of immediate hypersensitivity (allergic) diseases are
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