Mayo Test Catalog, (Sorted By Test Name) - Mayo Medical ...

NICRU
60442
considered to be an incidental finding as no correlation with toxic events has been identified. Routine
monitoring of patients undergoing dialysis is currently not recommended. Breathing dust high in nickel
content has been associated with development of neoplasms of the respiratory system and nasal sinuses.
Most reactions to nickel are localized skin sensitivity and allergic skin disorders that occur on contact
with nickel-containing alloys. These reactions do not correlate to blood concentrations; patients
experiencing skin sensitivity reactions to nickel are likely to have normal circulating concentrations of
nickel.
Useful For: Urine nickel is the test of choice for detecting nickel toxicity in patients exposed to
nickel carbonyl
Interpretation: Values >2.0 ng/mL represent possible environmental or job-related exposure. Toxic
concentrations are > or =10 ng/mL. Normal values are based on a Mayo Clinic study using healthy
volunteers. Toxic values have been deduced from observation and unpublished internal study. Clinical
concern about nickel toxicity should be limited to patients with potential for exposure to toxic nickel
compounds such as nickel carbonyl. Hypernickelemia, in the absence of exposure to that specific form
of nickel, may be an incidental finding or could be due to specimen contamination.
Reference Values: