Mayo Test Catalog, (Sorted By Test Name) - Mayo Medical ...

FCMVG
91695
LCMV
81240
CMV infection in HSCT. Biol Blood Marrow Transplant 2005;15(2):8-9 6. Boeckh M: Prevention of late
CMV infection in HSCT. Biol Blood Marrow Transplant 2005;15(2):9-11 7. Li CR, Greenberg PD,
Gilbert MJ, et al: Recovery of HLA-restricted CMV-specific T cell responses after allogeneic bone
marrow transplant: correlation with CMV disease and effect of ganciclovir prophylaxis. Blood
1994;83(7):1971-1979 8. Carmichael KF, Abayomi A: Analysis of diurnal variation of lymphocyte
subsets in healthy subjects and its implication in HIV monitoring and treatment. 15th Intl Conference on
AIDS, Bangkok, Thailand, 2004, Abstract # B11052 9. Dimitrov S, Benedict C, Heutling D, et al:
Cortisol and epinephrine control opposing circadian rhythms in T-cell subsets. Blood 2009 (prepublished
online March 17, 2009) 10. Dimitrov S, Lange T, Nohroudi K, Born J: Number and function of
circulating antigen presenting cells regulated by sleep. Sleep 2007;30:401-411 11. Kronfol Z, Nair M,
Zhang Q, et al: Circadian immune measures in healthy volunteers: relationship to
hypothalamic-pituitary-adrenal axis hormones and sympathetic neurotransmitters. Pyschosomatic
Medicine 1997;59:42-50 12. Malone JL, Simms TE, Gray GC, et al: Sources of variability in repeated
T-helper lymphocyte counts from HIV 1-infected patients: total lymphocyte count fluctuations and
diurnal cycle are important. J AIDS, 1990;3:144-151 13. Paglieroni TG, Holland PV: Circannual variation
in lymphocyte subsets, revisited. Transfusion 1994;34:512-516
Cytomegalovirus (CMV) Genotype
Reference Values:
UL97 Mutation/UL54 Mutation: Not Detected
Ganciclovir (GCV)/Foscarnet (PFA)/Cidofovir (CDV): Not Predicted
The method used in this test is PCR and sequencing of the
phosphotransferase (UL 97) gene and the polymerase (UL 54) gene
of CMV.
Test Performed by: Quest Diagnostics Nichols Institute 33608 Ortega Highway
San Juan Capistrano, CA 92690-6130
Cytomegalovirus (CMV), Molecular Detection, PCR
Clinical Information: Infection with cytomegalovirus (CMV) is a significant cause of morbidity
and mortality in transplant recipients and other immunocompromised hosts, as well as neonates.
Infection may involve multiple organs including the brain, lung, liver, and gastrointestinal tract.
Useful For: Rapid qualitative detection of cytomegalovirus DNA
Interpretation: Detection of cytomegalovirus (CMV) DNA in a specimen supports the clinical
diagnosis of infection due to this virus. Studies indicate that CMV DNA is not detected by PCR in
cerebrospinal fluid from patients without central nervous system disease caused by this virus.
Reference Values:
Not applicable
Clinical References: 1. Compston LI, Sarkodie F, Owusu-Ofori S, et al: Prevalence of persistent
and latent viruses in untreated patients infected with HIV-1 from Ghana, West Africa. J Med Virol 2009
Nov;81(11):1860-1868 2. Hudnall SD, Chen T, Allison P, et al: Herpesvirus prevalence and viral load
in healthy blood donors by quantitative real-time polymerase chain reaction. Transfusion
2008;48(6):1180-1187 3. Broccolo F, Iulioano R, Careddu AM, et al: Detection of lymphotropic
herpesvirus DNA by polymerase chain reaction in cerebrospinal fluid of AIDS patients with
neurological disease. Acta Virol 2000 June-August;44(3):137-143 4. Prosch S, Schielke E, Reip A, et
al: Human cytomegalovirus (HCMV) encephalitis in an immunocompetent young person and diagnostic
reliability of HCMV DNA PCR using cerebrospinal fluid of nonimmunosuppressed patients. J Clin
Microbiol 1998 December;36(12):3636-3640 5. Sia IG, Patel R: New strategies for prevention and
therapy of cytomegalovirus infection and disease in solid-organ transplant recipients. Clin Microbiol
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