Mayo Test Catalog, (Sorted By Test Name) - Mayo Medical ...

BRUC
8077
BRUCB
87345
recent infection is suspected, a new specimen should be tested after 7 to 14 days.
Reference Values:
IgG SCREEN
Negative (reported as positive, negative, or equivocal)
IgM SCREEN
Negative (reported as positive, negative, or equivocal)
Clinical References: 1. Corbel MJ: Brucellosis: an overview. Emerg Infect Dis 1997;3:213-221 2.
Public health consequences of a false-positive laboratory test result for Brucella--Florida, Georgia, and
Michigan, 2005, MMWR Morb Mortal Wkly Rep June 6;2008/57(22);603-605 3. Araj GF, Lulu AR,
Saadah MA, et al: Rapid diagnosis of central nervous system brucellosis by ELISA. J Neuroimmunol
1986;12:173-182
Brucella Culture
Clinical Information: Brucella are facultative intracellular gram negative staining bacilli capable
of producing the disease "brucellosis" in humans. Human disease likely is acquired by contact with
animals infected with the organism (Brucella abortus, Brucella suis, Brucella melitensis, and
occasionally Brucella canis) either by direct contact or by ingestion of meat or milk. The signs and
symptoms associated with brucellosis may include fever, night sweats, chills, weakness, malaise,
headache, and anorexia. The physical examination may reveal lymphadenopathy and
hepatosplenomegaly. A definitive diagnosis of brucellosis is made by recovering the organism from
blood, fluid (including urine), or tissue specimens.
Useful For: Diagnosis of brucellosis
Interpretation: Isolation of a Brucella species indicates infection. Cultures of blood and/or bone
marrow are positive in 70% to 90% of acute Brucella infections, but much less so in subacute or chronic
infections. In these latter instances, culture yield is highest from the specific tissue involved, or serology
may be necessary to establish diagnosis
Reference Values:
Negative (reported as positive or negative)
Clinical References: Mandell GL, Bennett JE, Dolin R: Mandell, Douglas, and Bennett's
Principles and Practice of Infectious Diseases. 4th edition. New York, Churchill Livingstone, 1995, pp
2053-2060
Brucella Culture, Blood
Clinical Information: Brucella are facultative intracellular gram negative staining bacilli capable
of producing the disease "brucellosis" in humans. Human disease likely is acquired by contact with
animals infected with the organism (Brucella abortus, Brucella suis, Brucella melitensis, and
occasionally Brucella canis) either by direct contact or by ingestion of meat or milk. The signs and
symptoms associated with brucellosis may include fever, night sweats, chills, weakness, malaise,
headache, and anorexia. The physical examination may reveal lymphadenopathy and
hepatosplenomegaly. A definitive diagnosis of brucellosis is made by recovering the organism from
blood, fluid (including urine), or tissue specimens.
Useful For: Diagnosis of brucellosis
Interpretation: Isolation of a Brucella species indicates infection. Cultures of blood and/or bone
marrow are positive in 70% to 90% of acute Brucella infections, but much less so in subacute or chronic
infections. In these latter instances, culture yield is highest from the specific tissue involved, or serology
may be necessary to establish diagnosis
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