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Mayo Test Catalog, (Sorted By Test Name) - Mayo Medical ...

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FKAN<br />

90069<br />

KETAU<br />

89443<br />

FKEBS<br />

91887<br />

Clinical References: 1. Meitinger T, Heye B, Petit C, et al: Definitive localization of X-linked<br />

Kallmann syndrome (hypogonadotropic hypogonadism and anosmia) to Xp22.3: close linkage to the<br />

hypervariable repeat sequence CRI-S232. Am J Hum Genet 1990 Oct;47(4):664-669 2. Weissortel R,<br />

Strom TM, Dorr HG, et al: Analysis of an interstitial deletion in a patient with Kallmann syndrome,<br />

X-linked ichthyosis and mental retardation. Clin Genet 1998 Jul;54(1):45-51<br />

Kanamycin Level, BA<br />

Reference Values:<br />

Peak levels, IM or IV, 1 hr: 22 mcg/mL<br />

Trough levels, IM or IV, 8 hrs: 3.2 mcg/mL<br />

Any undisclosed antimicrobials might affect the results.<br />

<strong>Test</strong> Performed <strong>By</strong>: Focus Diagnostics, Inc<br />

5785 Corporate Avenue<br />

Cypress, CA 90630-4750<br />

Ketamine and Metabolite Confirmation, Urine<br />

Clinical Information: Ketamine has been used in the United States as an anesthetic induction agent<br />

since 1972. The drug acts by noncompetitive antagonism of the N-methyl-D-aspartate (NMDA)-type<br />

glutamate receptors.(1,2) Ketamine has become a popular street drug because of its hallucinogenic<br />

effects.(3) Ketamine has a half-life of 3 to 4 hours, and is metabolized to norketamine.(3) The effects<br />

from ketamine last from 1 to 5 hours, and ketamine and/or norketamine can be detected in the urine for a<br />

period of 1 to 2 days following use.(4)<br />

Useful For: Detection and confirmation of ketamine use<br />

Interpretation: The presence of ketamine and/or norketamine >25 ng/mL is a strong indicator that the<br />

patient has used ketamine.<br />

Reference Values:<br />

Negative<br />

Clinical References: 1. Ujhelyi MR, Robert S, Cummings DM, et al: Influence of digoxin immune<br />

Fab therapy and renal dysfunction on the disposition of total and free digoxin. Ann Intern Med<br />

1993;119:273-277 2. Goodman & Gilman's: The Pharmacological Basis of Therapeutics. 10th edition.<br />

New York. McGraw-Hill Book Company, 2001 3. Baselt RC. Disposition of Toxic Drugs and Chemicals<br />

in Man. 7th edition. Foster City, CA. Biomedical Publications, 2004 pp 1254 4. Mozayani A:<br />

Ketamine-Effects on human performance and behavior. Forensic Sci Rev 2002;14:123-131<br />

Ketamine and Metabolite Screen/Confirmation, Serum/Plasma<br />

Reference Values:<br />

Reporting limit determined each analysis<br />

Units: ng/mL<br />

Ketamine:<br />

Synonym(s): Ketalar<br />

Reported levels during anesthesia: 500-6500 ng/mL<br />

Norketamine:<br />

Synonym(s): Ketamine Metabolite<br />

Current as of January 3, 2013 2:22 pm CST 800-533-1710 or 507-266-5700 or <strong>Mayo</strong><strong>Medical</strong>Laboratories.com Page 1074

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