Mayo Test Catalog, (Sorted By Test Name) - Mayo Medical ...

BBLD
8082
CFRC
89653
infections. Many Bacterioides produce beta-lactamase and are resistant to penicillins and cephalosporins.
Imipenem, metronidazole, and clindamycin are effective agents although resistance to clindamycin is
increasing.
Useful For: Diagnosing anaerobic bacterial infections
Interpretation: Isolation of anaerobes in significant numbers from well collected specimens
including blood, other normally sterile body fluids, or closed collections of purulent fluid indicates
infection with that (those) organism(s).
Reference Values:
Not applicable
Clinical References: Finegold SM, George WL: Anaerobic Infections in Humans. San Diego, CA,
Academic Press, 1989
Bacterial Culture, Blood
Clinical Information: When bacteria multiply at a rate that exceeds removal by phagocytes,
bacteremia results. The clinical pattern of bacteremia may be transient, intermittent, or continuous.
Transient bacteremia often occurs after manipulative procedures (dental procedures, cystoscopy) or
surgery in contaminated areas of the body. Undrained abscesses (intraabdominal, pelvic, hepatic) may
result in intermittent bacteremia. A hallmark feature of subacute bacterial endocarditis is a continuous
bacteremia. The sources of bacteremia are the genitourinary tract (25%), the respiratory tract (20%),
abscesses (10%), surgical wounds (5%), the biliary tract (5%), other known sites (10%), and unknown
sites (25%).
Reference Values:
No growth
Identification of all organisms
Clinical References: Mandell GL, Bennett JE, Dolin R: In Mandell, Douglas, and Bennett's
Principles and Practice of Infectious Diseases. Sixth edition. New York, NY, Churchill Livingstone,
2005, pp. 906-926.
Bacterial Culture, Cystic Fibrosis, Respiratory
Clinical Information: Life expectancy of patients with cystic fibrosis (CF) has increased steadily
over the past 50 years, in large part due to improvements in the management of lung disease in this
patient population. Still, chronic lung infection is responsible for 75% to 85% of deaths in patients with
CF. Appropriate treatment for the causative organism can reduce morbidity and mortality. The number
of microbial species associated with CF lung disease is relatively limited. These include Pseudomonas
aeruginosa (mucoid and nonmucoid), Staphylococcus aureus, Burkholderia cepacia complex,
Stenotrophomonas maltophilia, other nonfermenting gram-negative rods, Haemophilus influenzae, and
Streptococcus pneumoniae. Nontuberculous mycobacteria and Aspergillus species may also play a role
in CF lung disease, in addition to common respiratory viruses. This culture, which is specifically
designed for CF patients, utilizes conventional and additional selective media (compared to non-CF
respiratory cultures) to isolate bacteria commonly associated with pulmonary disease in CF patients. In
selected centers, lung transplantation is performed on CF patients. This test is appropriate for lung
transplant patients with underlying CF because they can continue to harbor the same types of organisms
as they did pretransplantation. CF patients may be colonized or chronically infected by these organisms
over a long period of time.
Useful For: Detection of aerobic bacterial pathogens from cystic fibrosis patient specimens
Interpretation: A negative test result is no growth of bacteria or growth of only usual flora. A
negative result does not rule out all causes of infectious lung disease (see "Cautions"). For positive test
results, pathogenic bacteria are identified. Because cystic fibrosis (CF) patients may be colonized or
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