Mayo Test Catalog, (Sorted By Test Name) - Mayo Medical ...

SPN
8047
FPOLC
57265
sensitive (21% more sensitive than direct detection using fluorescent calcofluor white stain), specific,
and objective detection of Pneumocystis from bronchoalveolar lavage fluid and other specimens.
Useful For: Preferred test for detection of Pneumocystis
Interpretation: A positive result indicates the presence of Pneumocystis DNA. A negative result
indicates the absence of detectable Pneumocystis DNA.
Reference Values:
Not applicable
Clinical References: 1. Cushion MT: Pneumocystis. In Manual of Clinical Microbiology. 8th
edition. Edited by PR Murray, EJ Baron, JH Jorgensen, et al: Washington, DC, ASM Press, 2003, pp
1712-1725 2. Maskell NA, Waine DJ, Lindley A, et al: Asymptomatic carriage of Pneumocystis jiroveci
in subjects undergoing bronchoscopy: a prospective study. Thorax July 2003;58(7):594-597 3. Miller RF,
Ambrose HE, Wakefield AE: Pneumocystis carinii f. sp. hominis DNA in immunocompetent health care
workers in contact with patients with P. carinii pneumonia. J. Clin. Microbiol November
2001;39(11):3877-3882 4. Takahashi T, Goto M, Endo T, et al: Pneumocystis carinii carriage in
immunocompromised patients with and without human immunodeficiency virus infection. J Med
Microbiol July 2002;51(7):611-614 5. Vargas SL, Hughes WT, Santolaya ME, et al: Search for primary
infection by Pneumocystis carinii in a cohort of normal, healthy infants. Clin Infect Dis March
2001;32(6):855-861 6. Wakefield AE, Lindley AR, Ambrose HE, et al: Limited asymptomatic carriage of
Pneumocystis jiroveci in human immunodeficiency virus-infected patients. J Infect Dis
2003;187(6):901-908
Pneumocystis Smear
Clinical Information: Pneumocystis jiroveci is one of the major microbial pathogens associated with
opportunistic pulmonary infections in patients receiving immunosuppressive therapy or with immune
deficiencies. Presently, the most common means to diagnose P. jiroveci infection is by microscopic
detection of the organisms in specimens such as bronchoalveolar lavage, open lung biopsy tissue, induced
sputum and transtracheal aspirate.
Useful For: Diagnosis of Pneumocystis jiroveci pneumonia
Interpretation: Negative: no cysts observed Positive: cysts present
Reference Values:
Negative
Clinical References: 1. Olsson M, Elvin K, Linder E, et al: [Pneumocystis carinii is still a dangerous
opportunist. The infection is continuously a threat to immunocompromised patients]. [Review] [60 refs]
[Swedish] [Journal Article. Review, Tutorial] Lakartidningen 1999 Jan27;96(4):328-31 2. Shelhamer JH,
Gill VJ, Quinn TC, et al: The laboratory evaluation of opportunistic pulmonary infections. [Review] [94
refs] [Consensus Development Conference, NIH. Journal Article. Review] Annals of Internal Medicine
1996 Mar 15;124(6):585-99 3. Kim YK, Parulekar S, Yu PK, et al: Evaluation of Calcofluor white stain
for detection of Pneumocystis carinii. Diagn Microbio Infect Dis 1990;13:307-310. Baselski VS, Robison
MK, Pifer LW, Woods DR: Rapid detection of Pneumocystis carinii in bronchoalveolar lavage samples
by using Cellufluor staining. J Clin Microbiol 1990;28:393-394.
Poliovirus (Types 1-3) Ab, CSF
Reference Values:
REFERENCE RANGE: