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Mayo Test Catalog, (Sorted By Test Name) - Mayo Medical ...

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Excision Circles [TREC] Analysis for Immune Reconstitution) provides a comprehensive assessment of<br />

thymopoiesis. Conversely, increases in CD8 RTEs are of no clinical significance, and do not indicate a<br />

pathologic finding. Since CD8 RTEs is a rare population, small changes in serial measurements may<br />

result in some values being above the reference range; however, as noted, increases in CD8 RTEs do<br />

not have clinical significance. To evaluate immune reconstitution or recovery of thymopoiesis<br />

post-T-cell depletion due to HSCT, immunotherapy, or other clinical conditions, it is essential to<br />

serially measure CD4, CD8 RTE, and TREC levels. A consultative report is provided.<br />

Reference Values:<br />

CD4 T-CELL RECENT THYMIC EMIGRANTS (RTE)<br />

CD4 Absolute<br />

Males<br />

1 month-17 years: 153-1,745 cells/mcL<br />

18-70 years: 290-1,175 cells/mcL<br />

Females<br />

1 month-17 years: 582-1,630 cells/mcL<br />

18-70 years: 457-1,766 cells/mcL<br />

Reference values have not been established for patients that are 70 years of age.<br />

CD4 RTE %<br />

Males<br />

1 month-17 years: 19.4-60.9%<br />

18-25 years: 6.4-51.0%<br />

26-55 years: 6.4-41.7%<br />

56-70 years: 6.4-27.7%<br />

Females<br />

1 month-17 years: 25.8-68.0%<br />

18-25 years: 6.4-51.0%<br />

26-55 years: 6.4-41.7%<br />

56-70 years: 6.4-27.7%<br />

Reference values have not been established for patients that are 70 years of age.<br />

CD4 RTE Absolute<br />

Males<br />

1 month-17 years: 50.0-926.0 cells/mcL<br />

18-70 years: 42.0-399.0 cells/mcL<br />

Females<br />

1 month-17 years: 170.0-1,007.0 cells/mcL<br />

18-70 years: 42.0-832.0 cells/mcL<br />

Reference values have not been established for patients that are 70 years of age.<br />

CD8 T-CELL RTE<br />

CD8 Absolute<br />

1 month-17 years: 143-902 cells/mcL<br />

18-35 years: 208-938 cells/mcL<br />

36-55 years: 142-844 cells/mcL<br />

56-70 years: 58-680 cells/mcL<br />

Reference values have not been established for patients that are 70 years of age.<br />

CD8 RTE %<br />

1 month-17 years: 0.1-1.7%<br />

18-45 years: 0.0-0.6%<br />

46-70 years: 0.0-0.3%<br />

Reference values have not been established for patients that are

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