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Mayo Test Catalog, (Sorted By Test Name) - Mayo Medical ...

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DAU9<br />

505320<br />

DASM4<br />

60553<br />

Results of this test are confirmed and should be considered definitive. Specimens are normally kept for<br />

2 weeks after <strong>Mayo</strong> <strong>Medical</strong> Laboratories New England receipt date.<br />

Clinical References: Porter WF, Moyer TP: Clinical toxicology. In Tietz Textbook of Clinical<br />

Chemistry. Fourth edition. Edited by CA Burtis, ER Ashwood. Philadelphia, PA, WB Saunders Company,<br />

1993, pp 1155-1235<br />

Drugs of Abuse Screen, DAU9, Urine<br />

Clinical Information: This test uses immunologic testing for drugs by class and screens for the<br />

presence of amphetamines, barbiturates, benzodiazepines, cocaine, metabolite, methadone, opiates,<br />

phencyclidine, propoxyphene, and tetrahydrocannabinol in urine. Positive immunologic results are<br />

confirmed by gas chromatography-mass spectrometry (GC-MS) or liquid chromatography-tandem mass<br />

spectrometry (LC-MS/MS).<br />

Useful For: Detecting drug abuse involving amphetamines, barbiturates, benzodiazepines, cocaine,<br />

opiates, phencyclidine, tetrahydrocannabinol, methadone, and propoxyphene This test is intended to be<br />

used only by a qualified drug treatment counselor or physician.<br />

Interpretation: A positive result indicates that the patient has used the drugs detected in the recent<br />

past. For information about drug testing, including estimated detection times, see Drugs of Abuse <strong>Test</strong>ing<br />

at http://www.mayomedicallaboratories.com/articles/drug-book/index.html Creatinine and specific gravity<br />

are measured as indicators of specimen dilution.<br />

Reference Values:<br />

Negative<br />

The specific drug identified will be reported.<br />

EMIT cutoff concentrations<br />

Amphetamines: 500 ng/mL<br />

Barbiturates: 200 ng/mL<br />

Benzodiazepines: 200 ng/mL<br />

Cocaine (benzoylecgonine-cocaine metabolite): 150 ng/mL<br />

Methadone: 300 ng/mL<br />

Opiates: 300 ng/mL<br />

Phencyclidine: 25 ng/mL<br />

Propoxyphene: 300 ng/mL<br />

THC: 50 ng/mL<br />

Results of this test are confirmed and should be considered definitive. Specimens are normally kept for 2<br />

weeks after <strong>Mayo</strong> <strong>Medical</strong> Laboratories New England receipt date.<br />

Clinical References: Porter WF, Moyer TP: Clinical toxicology. In Tietz Textbook of Clinical<br />

Chemistry. Fourth edition. Edited by CA Burtis, ER Ashwood. Philadelphia, WB Saunders Company,<br />

1993, pp 1155-1235<br />

Drugs of Abuse Screen, Meconium 4<br />

Clinical Information: Illicit drug use during pregnancy is a major social and medical issue. Drug<br />

abuse during pregnancy is associated with significant perinatal complications, which include a high<br />

incidence of stillbirths, meconium-stained fluid, premature rupture of the membranes, maternal<br />

hemorrhage (abruption placenta or placenta praevia), and fetal distress.(1) In the neonate, the mortality<br />

rate, as well as morbidity (eg, asphyxia, prematurity, low birthweight, hyaline membrane distress,<br />

infections, aspiration pneumonia, cerebral infarction, abnormal heart rate and breathing problems, drug<br />

withdrawal) are increased.(1) The disposition of drug in meconium is not well understood. The proposed<br />

mechanism is that the fetus excretes drug into bile and amniotic fluid. Drug accumulates in meconium<br />

either by direct deposit from bile or through swallowing of amniotic fluid.(2) The first evidence of<br />

meconium in the fetal intestine appears at approximately the 10th to 12th week of gestation, and slowly<br />

moves into the colon by the 16th week of gestation.(3) Therefore, the presence of drugs in meconium has<br />

Current as of January 3, 2013 2:22 pm CST 800-533-1710 or 507-266-5700 or <strong>Mayo</strong><strong>Medical</strong>Laboratories.com Page 648

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