Mayo Test Catalog, (Sorted By Test Name) - Mayo Medical ...

DOXA
61644
ROXU
85631
likelihood of allergic disease as opposed to other etiologies and defines the allergens that may be
responsible for eliciting signs and symptoms. The level of IgE antibodies in serum varies directly with the
concentration of IgE antibodies expressed as a class score or kU/L.
Reference Values:
Class IgE kU/L Interpretation
0 Negative
1 0.35-0.69 Equivocal
2 0.70-3.49 Positive
3 3.50-17.4 Positive
4 17.5-49.9 Strongly positive
5 50.0-99.9 Strongly positive
6 > or =100 Strongly positive Reference values
apply to all ages.
Clinical References: Homburger HA: Allergic diseases. In Clinical Diagnosis and Management
by Laboratory Methods. 21st edition. Edited by McPherson RA, Pincus MR. WB Saunders, Publ, New
York, Chapter 53, Part VI, pp. 961-971, 2007
Oxalate Analysis in Hemodialysate
Clinical Information: Oxalate is a dicarboxylic acid, an end product of glyoxalate and glycerate
metabolism that is excreted in the urine where it is a common component of kidney stones (up to 85%).
Hyperoxaluria can be either genetic (eg, primary hyperoxaluria) or acquired/secondary (eg, enteric
hyperoxaluria), and can lead to nephrocalcinosis and renal failure. Monitoring the adequacy of oxalate
removal during hemodialysis can be useful in the management of patients with hyperoxaluria and renal
failure, particularly following transplantation.
Useful For: Determining of the amount of oxalate removed during a dialysis session Individualizing
the dialysis prescription of hyperoxaluric patients
Interpretation: A steady decrease in oxalate signal is expected through dialysis procedure. Signals
below 2 mcM should be considered ideal conditions. Total oxalate removed during a dialysis session
can be estimated by multiplying the concentration of oxalate in the dialysate by the oxalate flow rate for
each time period that the oxalate is measured.
Reference Values:
Not applicable
Clinical References: 1. Canavese C, Petrarulo M, Massarenti P, et al: Long-term, low-dose,
intravenous vitamin C leads to plasma calcium oxalate supersaturation in hemodialysis patients. Am J
Kidney Dis 2005 Mar;45(3):540-549 2. Koch GH, Strong FM. Determination of oxalate in urine. Anal
Biochem 1969 Jan;27(1):162-171 3. Marangella M, Petrarulo M, Mandolfo S, et al: Plasma profiles and
dialysis kinetics of oxalate in patients receiving hemodialysis. Nephron 1992;60(1):74-80 4. Marangella
M, Vitale C, Petrarulo M, et al. Bony content of oxalate in patients with primary hyperoxaluria or
oxalosis-unrelated renal failure. Kidney Int 1995;48(1):182-187
Oxalate, Pediatric, Random, Urine
Clinical Information: Oxalate is an end product of glyoxalate and glycerate metabolism. Humans
have no enzyme capable of degrading oxalate, so it must be eliminated by the kidney. In tubular fluid,
oxalate can combine with calcium to form calcium oxalate stones. In addition, high concentrations of
oxalate may be toxic for renal cells. Increased urinary oxalate excretion results from inherited enzyme
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