Mayo Test Catalog, (Sorted By Test Name) - Mayo Medical ...

LVZV
81241
FVEGF
91765
Interpretation: A positive IgM result indicates a recent infection with varicella-zoster virus (VZV).
A negative result does not rule out the diagnosis of VZV infection. The specimen may have been drawn
before the appearance of detectable antibodies. Negative results in suspected early VZV infection
should be followed by testing a new specimen in 2 to 3 weeks.
Reference Values:
Negative (reported as positive or negative)
Clinical References: 1. Kennedy PG: Latent varicella-zoster virus is located predominantly in
neurons in human trigeminal ganglia. Proc Natl Acad Sci USA 1998;95:4658-4662 2. McPherson RE:
Herpes zoster ophthalmicus and the immunocompromised host: a case report and review. J Am Optom
Assoc 1997;68:527-538 3. Papanicolaou GA, Meyers BR, Fuchs WS, et al: Infectious ocular
complications in orthotopic liver transplant patients. Clin Infect Dis 1997;24:1172-1177 4. Flamholc L:
Neurological complications in herpes zoster. Scand J Infect Dis 1996;100:35-40
Varicella-Zoster Virus, Molecular Detection, PCR
Clinical Information: Varicella-zoster virus (VZV) causes both varicella (chickenpox) and herpes
zoster (shingles). VZV produces a generalized vesicular rash on the dermis (chickenpox) in normal
children, usually before 10 years of age. After primary infection with VZV, the virus persists in latent
form and may emerge (usually in adults 50 years of age and older) clinically to cause a unilateral
vesicular eruption, generally in a dermatomal distribution (shingles).
Useful For: Rapid (qualitative) detection of varicella-zoster virus DNA in clinical specimens for
laboratory diagnosis of disease due to this virus
Interpretation: Detection of varicella-zoster virus DNA in clinical specimens supports the clinical
diagnosis of infection due to this virus.
Reference Values:
Not applicable
Clinical References: 1. Cinque P, Bossolasco S, Vago L, et al: Varicella-zoster virus (VZV) DNA
in cerebrospinal fluid of patients infected with human immunodeficiency virus: VZV disease of the
central nervous system or subclinical reactivation of VZV infection? Clin Infect Dis
1997;25(3):634-639 2. Brown M, Scarborough M, Brink N, et al: Varicella zoster virus-associated
neurological disease in HIV-infected patients. Int J STD AIDS 2001;12(2):79-83 3. Studahl M, Hagberg
L, Rekabdar E, Bergstrom T: Herpesvirus DNA detection in cerebrospinal fluid: differences in clinical
presentation between alpha-, beta-, and gamma-herpesviruses. Scand J Infect Dis 2000;32(3):237-248 4.
Iten A, Chatelard P, Vuadens P, et al: Impact of cerebrospinal fluid PCR on the management of
HIV-infected patients with varicella-zoster virus infection of the central nervous system. J Neurovirol
1999;5(2):172-180
Vascular Endothelial Growth Factor (VEGF), ELISA
Reference Values:
VEGF: 31 – 86 pg/mL
This test was performed using a kit that has not been approved or cleared by the FDA. The analytical
performance characteristics of this test have been determined by Quest Diagnostics Nichols Institute.
This test should not be used for diagnosis without confirmation by other medically established means.
Test Performed by: Quest Diagnostics Nichols Institute
33608 Ortega Highway
San Juan Capistrano, CA 92690-6130
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