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Mayo Test Catalog, (Sorted By Test Name) - Mayo Medical ...

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FNTPX<br />

57308<br />

FINA<br />

91447<br />

overlap in values between UP and systemic mastocytosis, and urinary NMH measurements should not be<br />

relied upon alone in distinguishing localized from systemic disease. Up to 25% variability in spot-urine<br />

excreted levels may be observed, making 24-hour urine collections preferable for cases with borderline<br />

results. Children have higher NMH levels than adults. <strong>By</strong> the age of 16 adult levels have been reached.<br />

Reference Values:<br />

0-5 years: 120-510 mcg/g creatinine<br />

6-16 years: 70-330 mcg/g creatinine<br />

>16 years: 30-200 mcg/g creatinine<br />

Clinical References: 1. Roberts LJ II, Oates JA: Disorders of vasodilator hormones: the carcinoid<br />

syndrome and mastocytosis. In Williams Textbook of Endocrinology. 8th edition. Edited by JD Wilson,<br />

DW Foster. Philadelphia, WB Saunders Company, 1992, pp 1625-1634 2. Akin C, Metcalfe DD:<br />

Mastocytosis. In Allergic Skin Disease: A Multidisciplinary Approach. Edited by DYM Leung, MW<br />

Greaves. New York. Marcel Dekker, Inc., 2000, pp 337-352 3. Keyzer JJ, de Monchy JG, van<br />

Doormaal JJ, van Voorst Vader PC: Improved diagnosis of mastocytosis by measurement of urinary<br />

histamine metabolites. N Engl J Med 1983;309(26):1603-1605 4. Heide R, Riezebos P, van<br />

Toorenbergen AW, et al: Predictive value of urinary N-methylhistamine for bone marrow involvement<br />

in mastocytosis. J Invest Dermatol 2000;115(3):587 5. Van Gysel D, Oranje AP, Vermeiden I, et al:<br />

Value of urinary N-methylhistamine measurements in childhood mastocytosis. J Am Acad Derm<br />

1996;35(4):556-558<br />

N-Telopeptide, Cross-Linked, Serum<br />

Reference Values:<br />

Adult Male: 5.4-24.2 nM BCE Premenopausal, Adult Female: 6.2-19.0 nM BCE<br />

The target value for treated post-menopausal adult<br />

females is the same as the premenopausal reference<br />

interval.<br />

BCE = Bone Collagen Equivalent<br />

<strong>Test</strong> Performed by: ARUP Laboratories<br />

500 Chipeta Way<br />

Salt Lake City, UT 84108<br />

NAbFeron (IFN-B) Neutralizing Antibody<br />

Useful For: Detection of antibodies to interferon-B-1<br />

Reference Values:<br />

Normal titer: or = 20 - < or = 60<br />

High titer: >60<br />

<strong>Test</strong> Performed <strong>By</strong>: Athena Diagnostics<br />

377 Plantation St.<br />

Four Biotech Park<br />

Worcester, MA 01605<br />

Clinical References: Grossberg et all. J Interferon Research 1988; 8: 5-7 Grossberg et al.<br />

Biotherapy (in press) 1997 Grossberg et al. In: Manual of Clinical Laboratory Immunology,1986 3rd ed.<br />

295-299 WHO Technical Report Series 687, 35-60, 1983 Betaseron prescribing information, Berlex<br />

Rebif prescribing information, Serono AVONEX product insert, Biogen 1996 Sibley et al. Neurology<br />

1996; 47: 889-894 Paty et al. Neurology 1996; 47: 865-866<br />

Current as of January 3, 2013 2:22 pm CST 800-533-1710 or 507-266-5700 or <strong>Mayo</strong><strong>Medical</strong>Laboratories.com Page 1289

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