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Mayo Test Catalog, (Sorted By Test Name) - Mayo Medical ...

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FHFIB<br />

91402<br />

Reference Values:<br />

Negative<br />

Interpretation depends on clinical setting.<br />

See Viral Hepatitis Serologic Profiles in Special Instructions.<br />

Clinical References: 1. Carithers RL, Marquardt A, Gretch DR: Diagnostic testing for hepatitis C.<br />

Semin Liver Dis 2000;20(2):159-171 2. Alter MJ, Kuhnert WL, Finelli L: Centers for Disease Control<br />

and Prevention: guidelines for laboratory testing and result reporting of antibody to hepatitis C virus.<br />

MMWR Morb Mortal Wkly Rep 2003;52(RR-3):1-13 3. Germer JJ, Zein NN: Advances in the molecular<br />

diagnosis of hepatitis C and their clinical implications. <strong>Mayo</strong> Clin Proc 2001;76(9):911-920 4. Pawlotsky<br />

JM: Use and interpretation of virological tests for hepatitis C. Hepatology 2002;36:S65-S73<br />

Hepatitis C Virus (HCV) FibroSURE<br />

Useful For: Assessment of Liver status following a diagnosis of HCV. Baseline determination of liver<br />

status before initiating HCV therapy. Post- treatment assessment of liver status six months after<br />

completion of therapy. Non-invasive assessment of liver status in patient who are at increased risk of<br />

complications from a liver biopsy.<br />

Reference Values:<br />

TESTS REFERENCE INTERVAL<br />

HCV FibroSURE Results:<br />

Fibrosis Score 0.00 - 0.21<br />

Fibrosis Stage<br />

Necroinflammat Activity Score 0.00 - 0.17<br />

Necroinflammat Activity Grade<br />

Analysis:<br />

Alpha-2-Macroglobulins, Qn 110 - 276 mg/dL<br />

Haptoglobin 34 – 200 mg/dL<br />

Apolipoprotein A-1 Females: 110 – 205 mg/dL<br />

Males: 110 – 180 mg/dL<br />

Bilirubin, Total<br />

Newborns, term and near term:<br />

24 hours old: 0.0 – 8.0 mg/dL<br />

48 hours old: 0.0 – 12.2 mg/dL<br />

72 hours old: 0.0 – 15.6 mg/dL<br />

96 hours to 1 month old: 0.0 – 1.2 mg/dL<br />

Children 1 month and older and<br />

Adults: 0.0 – 1.2 mg/dL<br />

GGT Females: 0 – 60 IU/L<br />

Males: 0 – 65 IU/L<br />

ALT (SGPT) Females: 0 - 40 IU/L<br />

Males: 0 – 55 IU/L<br />

Interpretations:<br />

Quantitative results of 6 biochemical tests are analyzed using a<br />

computational algorithm to provide a quantitative surrogate marker<br />

(0.0-1.0) for liver fibrosis (METAVIR F0-F4) and for<br />

necroinflammatory activity (METAVIR A0-A3).<br />

Fibrosis Scoring:<br />

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