Mayo Test Catalog, (Sorted By Test Name) - Mayo Medical ...

FRFIT
90330
RASE
82366
sensitization to particular allergens prior to beginning immunotherapy, and to investigate the specificity of
allergic reactions to insect venom allergens, drugs, or chemical allergens.
Interpretation: Detection of IgE antibodies in serum (Class 1 or greater) indicates an increased
likelihood of allergic disease as opposed to other etiologies and defines the allergens that may be
responsible for eliciting signs and symptoms. The level of IgE antibodies in serum varies directly with
the concentration of IgE antibodies expressed as a class score or kU/L.
Reference Values:
Class IgE kU/L Interpretation
0 Negative
1 0.35-0.69 Equivocal
2 0.70-3.49 Positive
3 3.50-17.4 Positive
4 17.5-49.9 Strongly positive
5 50.0-99.9 Strongly positive
6 > or =100 Strongly positive Reference values
apply to all ages.
Clinical References: Homburger HA: Allergic diseases. In Clinical Diagnosis and Management
by Laboratory Methods. 21st edition. Edited by RA McPherson, MR Pincus. New York, WB Saunders
Company, 2007, Chapter 53, Part VI, pp 961-971
Rabies Antibody Endpoint
Interpretation: Qualitative results. For those who want to know if they need a booster of rabies
vaccine. RFFIT stands for Rapid Fluorescent Foci Inhibition Test. It is a serum neutralization
(inhibition) test, which means it measures the ability of rabies specific antibodies to neutralize rabies
virus and prevent the virus from infecting cells. The antibodies are called rabies virus neutralizing
antibodies (RVNA).
Reference Values:
Reportable range is 0.1 to 15.0 IU/mL
Less than 0.1 IU/mL: Below detection limit
>15.0 IU/mL or >14.0 IU/mL: Above reportable range
In humans a result of 0.5 IU/mL or higher is considered acceptable according to the World Health
Organization (WHO) guidelines; see WHO and Advisory Committee on Immunization Practices
documents for additional guidance.
Test Performed by: RFFIT/K-State Rabies Laboratory
Manhattan/K-State Innovation Center
2005 Research Park Circle
Manhattan, KS 66502
Rape Seed, IgE
Clinical Information: Clinical manifestations of immediate hypersensitivity (allergic) diseases are
caused by the release of proinflammatory mediators (histamine, leukotrienes, and prostaglandins) from
immunoglobulin E (IgE)-sensitized effector cells (mast cells and basophils) when cell-bound IgE
antibodies interact with allergen. In vitro serum testing for IgE antibodies provides an indication of the
immune response to allergen(s) that may be associated with allergic disease. The allergens chosen for
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