Mayo Test Catalog, (Sorted By Test Name) - Mayo Medical ...

FPSAU
91817
PACP
8019
biopsy does not rule-out prostate cancer. Up to 20% of men with negative biopsy results have
subsequently been found to have cancer. Based on free:total PSA ratio: the percent probability of
finding prostate cancer on a needle biopsy by age in years: Free:total PSA ratio 50-59 years 60-69 years
> or =70 years < or =0.10 49.2% 57.5% 64.5% 0.11-0.18 26.9% 33.9% 40.8% 0.19-0.25 18.3% 23.9%
29.7% >0.25 9.1% 12.2% 15.8%
Reference Values:
Age (Years) PSA Upper Limit (ng/mL)
< or =2.0
40-49 < or =2.5
50-59 < or =3.5
60-69 < or =4.5
70-79 < or =6.5
> or =80 < or =7.2 Females: not applicable FREE PSA Males: When
total PSA is in the range of 4.0-10.0 ng/mL, a free:total PSA
ratio < or =0.10 indicates 49% to 65% risk of prostate
cancer depending on age; a free:total PSA ratio >0.25
indicates a 9% to 16% risk of prostate cancer, depending on
age. Females: not applicable
Clinical References: 1. Oesterling JE, Jacobsen SJ, Chute CG, et al: Serum Prostate-Specific
Antigen in a Community-Based Population of Healthy Men. JAMA 1993 Aug 18; 270:860-864 2.
Catalona WJ, Smith DS, Wolfert RL, et al: Evaluation of percentage of free serum prostate-specific
antigen to improve specificity of prostate cancer screening. JAMA 1995:274(15);214-1220 3. Jacobsen
SJ, Bergstralh EJ, Guess HA, et al: Predictive properties of serum prostate-specific antigen testing in a
community-based setting. Arch Intern Med 1996;156:2462-2468 4. Oesterling JE, Jacobsen SJ, Klee GG,
et al: Free, complexed and total serum prostate specific antigen: the establishment of appropriate reference
ranges for their concentrations and ratios. J Urol 1995;154:1090-1095 5. Dworschack RT, Thiel RP,
Picolli SP. Clinical Evaluation of the free/total PSA ratio generated with the Elecsys Total and Free PSA
assays on the Elecsys 1010 and 2010 systems. Clin Chem 2001 Jun; 47 (6 Suppl S):A149. (Abstract)
Prostate-Specific Antigen, Ultrasensitive
Reference Values:
0.0 00 - 4.000 ng/mL
Roche ECLIA methodology
According to the American Urological Association, Serum PSA should decrease and remain at
undetectable levels after radical prostatectomy. The AUA defines biochemical recurrence as an initial
PSA value 0.200 ng/mL or greater followed by a subsequent confirmatory PSA value 0.200 ng/mL or
greater.
Values obtained with different assay methods or kits cannot be used interchangeably. Results cannot be
interpreted as absolute evidence of the presence or absence of malignant disease.
Test Performed by: LabCorp Burlington
1447 York Court
Burlington, NC 27215
Prostatic Acid Phosphatase (PAP), Serum
Clinical Information: Prostatic acid phosphatase (PAP), a glycoprotein synthesized by the prostate
Current as of January 3, 2013 2:22 pm CST 800-533-1710 or 507-266-5700 or MayoMedicalLaboratories.com Page 1496