Mayo Test Catalog, (Sorted By Test Name) - Mayo Medical ...

FROPI
57171
ROTA
8886
accompanied by renal involvement.(1,2) RNP is 1 of 4 autoantigens commonly referred to as extractable
nuclear antigens (ENAs). The other ENAs are SS-A/Ro, SS-B/La, and Sm. Each ENA is composed of 1
or more proteins associated with small nuclear RNA species (snRNP) ranging in size from 80 to
approximately 350 nucleotides. Antibodies to ENAs are common in patients with connective tissue
diseases (systemic rheumatic diseases) including LE, MCTD, Sjogren's syndrome, scleroderma (systemic
sclerosis), and polymyositis/dermatomyositis. See Connective Tissue Disease Cascade (CTDC) in Special
Instructions and Optimized Laboratory Testing for Connective Tissue Diseases in Primary Care: The
Mayo Connective Tissue Diseases Cascade in Publications.
Useful For: Evaluating patients with signs and symptoms of a connective tissue disease in whom the
test for antinuclear antibodies is positive
Interpretation: A positive result for RNP antibodies is consistent with a connective tissue disease.
Although strongly associated with connective tissue diseases, RNP antibodies are not considered a
"marker" for any particular disease except in the following situation: when found in isolation (ie,
dsDNA antibodies and Sm antibodies are not detectable), a positive result for RNP antibodies is
consistent with the diagnosis of mixed connective tissue disease.
Reference Values:
or =1.0 U (positive)
Reference values apply to all ages.
Clinical References: 1. Homburger H, Larsen S: Detection of specific antibodies. In Clinical
Immunology: Principles and Practice. 1st edition. Edited by R Rich, T Fleisher, B Schwartz, et al. St.
Louis, Mosby-Year Book, 1996, pp 2096-2109 2. Kotzin B, West S: Systemic lupus erythematosus. In
Clinical Immunology Principles and Practice. 2nd edition. Edited by R Rich, T Fleisher, W Shearer, et
al. St. Louis, Mosby-Year Book, 2001, pp 60.1-60.24
Ropivacaine, Serum/Plasma
Reference Values:
Following epidural administration 10 mg/hr, 20 mg/hr
and 30 mg/hr, mean plasma concentration of 0.39, 0.88,
1.19 mcg/mL at 21 hours respectively.
Bolus I.V. administration 84 mg/70 kg and 131 mg/70 kg,
peak plasma concentrations of 1.1 and 1.7 mcg/mL at
2 minutes respectively.
Test Performed by: NMS Labs
3701 Welsh Road
P.O. Box 433A
Willow Grove, PA 19090-0437
Rotavirus Antigen, Feces
Clinical Information: Rotavirus infection produces a spectrum of responses that vary from
subclinical infection, to mild diarrhea, to a severe and occasionally fatal dehydrating illness. Rotavirus
is the major cause of nonbacterial gastroenteritis, especially in infants and very young children (6
months-2 years of age). Among children hospitalized for gastroenteritis, up to 50% of the patient
specimens will give positive rotavirus test results. The shedding of rotavirus in feces is fairly common
among asymptomatic neonates. Endemic rotaviral infection is more likely to be symptomatic in babies
who require special care than in healthy, full-term infants. Rotaviruses pose a special threat to
individuals who are immunosuppressed for bone marrow transplantation and to elderly persons,
especially those living in nursing homes or other confined quarters. In other adults, rotavirus infections
usually are subclinical. In temperate climates, rotaviral infections are seasonal; they peak in frequency
during the winter months and are uncommon during the summer. Rotaviral gastroenteritis has
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