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Mayo Test Catalog, (Sorted By Test Name) - Mayo Medical ...

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PCPU<br />

80371<br />

FPHNZ<br />

90368<br />

PBAR<br />

Reference Values:<br />

Negative<br />

Positives are reported with a quantitative LC-MS/MS result.<br />

Cutoff concentrations<br />

PCP by LC-MS/MS: >10 ng/g<br />

Clinical References: 1. O'Brien CP: Drug addiction and drug abuse. In Goodman and Gilman's the<br />

Pharmacological Basis of Therapeutics. 11th edition. Edited by LL Brunton, JS Lazo, KL Parker.<br />

McGraw-Hill Book Company, Inc, 2006 2. Baselt RC: Phencyclidine. In Disposition of Toxic Drugs and<br />

Chemicals in Man. Eighth edition. Edited by RC Baselt. Foster City, CA, Biomedical Publications, 2008,<br />

pp 1735<br />

Phencyclidine Confirmation, Urine<br />

Clinical Information: Phencyclidine (PCP) is a drug of abuse. This compound affects diverse neural<br />

pathways and interacts with cholinergic, adrenergic, GABA-secreting, serotoninergic, opiate neuronal<br />

receptors, and gamma receptors. It has analgesic, anesthetic, and stimulatory effects, giving bizarre<br />

behavior, ranging from depression through catatonia, euphoria, violent rage, and hallucinations. Most<br />

fatalities result from its hypertensive effect. Diagnosis of PCP usage depends on drug screen. PCP is<br />

excreted in the urine.<br />

Useful For: Detection of drug abuse involving phencyclidine (angel dust, or angel hair)<br />

Interpretation: The presence of phencyclidine (PCP) in urine at concentrations >10 ng/mL is a strong<br />

indicator that the patient has used PCP.<br />

Reference Values:<br />

Negative<br />

Positives are reported with a quantitative GC-MS result.<br />

Cutoff concentrations<br />

Immunoassay screen:

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