Mayo Test Catalog, (Sorted By Test Name) - Mayo Medical ...

5361
bronchospasm) in infants and children less than 5 years due to food sensitivity (milk, egg, soy, and wheat
proteins) followed by respiratory disease (rhinitis and asthma) in older children and adults due to
sensitivity to inhalant allergens (dust mite, mold, and pollen inhalants).
Useful For: Testing for IgE antibodies may be useful to establish the diagnosis of an allergic disease
and to define the allergens responsible for eliciting signs and symptoms. Testing also may be useful to
identify allergens which may be responsible for allergic disease and/or anaphylactic episode, to confirm
sensitization to particular allergens prior to beginning immunotherapy, and to investigate the specificity
of allergic reactions to insect venom allergens, drugs, or chemical allergens.
Interpretation: Detection of IgE antibodies in serum (Class 1 or greater) indicates an increased
likelihood of allergic disease as opposed to other etiologies and defines the allergens that may be
responsible for eliciting signs and symptoms. The level of IgE antibodies in serum varies directly with
the concentration of IgE antibodies expressed as a class score or kU/L.
Reference Values:
Class IgE kU/L Interpretation
0 Negative
1 0.35-0.69 Equivocal
2 0.70-3.49 Positive
3 3.50-17.4 Positive
4 17.5-49.9 Strongly positive
5 50.0-99.9 Strongly positive
6 > or =100 Strongly positive Reference values
apply to all ages.
Clinical References: Homburger HA: Allergic diseases. In Clinical Diagnosis and Management
by Laboratory Methods. 21st edition. Edited by RA McPherson, MR Pincus. New York, WB Saunders
Company, 2007, Chapter 53, Part VI, pp 961-971
Cardiovascular or Cardiopulmonary Consultation, Autopsy
Clinical Information: Difficult cardiovascular and cardiopulmonary abnormalities, including
congenital anomalies, sometimes require the assistance of a cardiac pathologist. This evaluation is
offered to provide the careful dissection and diagnostic experience that may be needed for unusual or
rare cardiovascular or cardiopulmonary cases.
Useful For: Evaluation of congenital heart disease Evaluation of pulmonary hypertension Evaluation
of complex ischemic or valvular heart disease Evaluation of cardiomyopathies Evaluation of sudden
unexplained death Not for cases under litigation
Interpretation: This request will be processed as a consultation. Appropriate stain(s) will be
performed and a diagnositc interpretation provided.
Reference Values:
Abnormalities will be compared to reported reference values.
Clinical References: 1. Edwards WD: Congenital heart disease. In Anderson's Pathology. Edited
by J Linder, I Damjanov. St. Louis, MO, Mosby-Year Book, Inc., 1996, pp 1339-1396 2. Edwards WD:
Pathology of myocardial infarction and reperfusion. In Acute Myocardial Infarction. Edited by BJ
Gersh, S Rahimtoola. New York, Chapman and Hall, 1997, pp 16-50 3. Edwards WD:
Cardiomyopathies. Major Prob Path 1991;23:257-309
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