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Mayo Test Catalog, (Sorted By Test Name) - Mayo Medical ...

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DAAMP<br />

505341<br />

mass spectrometry (LC-MS/MS) with the exception of ethanol. Positive ethanol results are reported<br />

quantitatively directly from immunologic testing.<br />

Useful For: Detecting drug abuse involving amphetamines, barbiturates, benzodiazepines, cocaine,<br />

methadone, opiates, phencyclidine, propoxyphene, tetrahydrocannabinol, and ethanol This test is intended<br />

to be used only by a qualified drug treatment counselor or physician.<br />

Interpretation: A positive result indicates that the patient has used the drugs detected in the recent<br />

past. For information about drug testing, including estimated detection times, see Drugs of Abuse <strong>Test</strong>ing<br />

at http://www.mayomedicallaboratories.com/articles/drug-book/index.html Creatinine and specific gravity<br />

are measured as indicators of specimen dilution.<br />

Reference Values:<br />

Negative<br />

The specific drug identified will be reported.<br />

EMIT cutoff concentrations<br />

Amphetamines: 500 ng/mL<br />

Barbiturates: 200 ng/mL<br />

Benzodiazepines: 200 ng/mL<br />

Cocaine (benzoylecgonine-cocaine metabolite): 150 ng/mL<br />

Methadone: 300 ng/mL<br />

Opiates: 300 ng/mL<br />

Phencyclidine: 25 ng/mL<br />

Propoxyphene: 300 ng/mL<br />

THC: 50 ng/mL<br />

Ethanol: 10 mg/dL<br />

Results of this test are confirmed and should be considered definitive. Specimens are normally kept for 2<br />

weeks after <strong>Mayo</strong> <strong>Medical</strong> Laboratories New England receipt date.<br />

Clinical References: Porter WF, Moyer TP: Clinical toxicology. In Tietz Textbook of Clinical<br />

Chemistry. Fourth edition. Edited by CA Burtis, ER Ashwood. Philadelphia, PA, WB Saunders Company,<br />

1993, pp 1155-1235<br />

Drug of Abuse, Amphetamine Screen with GC-MS Confirmation,<br />

Urine<br />

Clinical Information: Amphetamines are sympathomimetic amines that stimulate central nervous<br />

system activity and, in part, suppress appetite. Phentermine, amphetamine, and methamphetamine are<br />

prescription drugs for weight loss. All of the other amphetamines are Class I (distribution prohibited)<br />

compounds. In addition to their medical use as anorectic drugs, they are used in the treatment of<br />

narcolepsy and minimal brain dysfunction. Because of their stimulant effects, the drugs are commonly<br />

sold illicitly and abused. Physiological symptoms associated with amphetamine overdose include elevated<br />

blood pressure, dilated pupils, hyperthermia, convulsions and acute psychosis.<br />

Useful For: Confirming drug abuse involving amphetamines such as amphetamine and<br />

methamphetamine, phentermine,, methylenediaoxyethylamphetamine (MDEA), and<br />

methylene-diaoxyethylamphetamine (MDA, a metabolite of MDMA and MDEA)<br />

Interpretation: The presence of amphetamines in urine concentrations >499 ng/mL is a strong<br />

indicator that the patient has used 1 of these drugs within the past 3 days. This test is very specific and<br />

does not produce a false-positive result when over-the-counter drugs are present in the specimen. This test<br />

will produce true-positive results for urine specimens collected from patients who are administered<br />

Adderall and Benzedrine (which contain amphetamine); Desoxyn and Vicks Inhaler (which contain<br />

methamphetamine); Selegiline (metabolizes to methamphetamine and amphetamine); and clobenzorex,<br />

famprofazone, fenethylline, fenproporex, and mefenorex (which are amphetamine pro-drugs).<br />

Reference Values:<br />

Negative<br />

Current as of January 3, 2013 2:22 pm CST 800-533-1710 or 507-266-5700 or <strong>Mayo</strong><strong>Medical</strong>Laboratories.com Page 638

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