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Mayo Test Catalog, (Sorted By Test Name) - Mayo Medical ...

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MCA<br />

9746<br />

FMPP<br />

91332<br />

Reference Values:<br />

An interpretive report will be provided.<br />

Clinical References: 1. Sieber OM, Lipton L, Crabtree M, et al: Multiple colorectal adenomas,<br />

classic adenomatous polyposis, and germ-line mutations in MYH. N Engl J Med 2003;348(9):791-799<br />

2. Wang L, Baudhuin LM, Boardman LA, Steenblock KJ, et al: MYH mutations in patients with<br />

attenuated and classic polyposis and with young-onset colorectal cancer without polyps.<br />

Gastroenterology 2004;127(1):9-16 3. Croitoru M, Cleary S, Di Nicola N, et al: Association between<br />

biallelic and monoallelic germline MYH gene mutations and colorectal cancer risk. J Natl Cancer Inst<br />

2004;96:1631-1634<br />

Myocardial Antibodies, Serum<br />

Clinical Information: Myocardial antibodies occur in the sera of patients who have acute<br />

rheumatic fever and carditis, or who have sustained mechanical (surgical or traumatic) or ischemic<br />

damage to myocardial tissue in the postcardiotomy and post myocardial infarction syndromes. In the<br />

"myocardial injury" syndromes, circulating myocardial antibodies become detectable 2 to 3 weeks after<br />

the injury in 30% (infarction) to 70% (postsurgical) of cases and remain detectable for 3 to 8 weeks.<br />

Myocardial antibodies have been detected in some patients with idiopathic cardiomyopathy. The<br />

pathogenic significance of myocardial antibodies is not known.<br />

Useful For: Evaluating patients suspected of having post cardiotomy or post myocardial infarction<br />

syndromes Evaluating patients suspected of having inflammatory cardiomyopathy<br />

Interpretation: Elevated in 30% of myocardial injury patients by the 2nd or 3rd week<br />

Reference Values:<br />

Negative<br />

If positive, results are titered.<br />

Reference values apply to all ages.<br />

Clinical References: Twomey SL, Bernett GE: Immunofluorescence method for detecting<br />

anti-myocardial antibodies, and its use in diagnosing heart disease. Clin Chem 1975;21:1903-1906<br />

Myocarditis/Pericarditis Panel<br />

Reference Values:<br />

MYOCARDITIS-PERICARDITIS PANEL<br />

COXSACKIE B(1-6) ANTIBODIES, SERUM<br />

REFERENCE RANGE: or = 1:32 are indicative of recent infection. Titers of 1:8 or 1:16 may be indicative of<br />

either past or recent infection, since CF antibody levels persist for only a few months. A four-fold or<br />

greater increase in titer between acute and convalescent specimens confirms the diagnosis. There is<br />

considerable crossreactivity among enteroviruses; however, the highest titer is usually associated with<br />

the infecting serotype.<br />

This test was developed and its performance characteristics have been determined by Focus<br />

Diagnostics. Performance characteristics refer to the analytical performance of the test.<br />

ECHOVIRUS ANTIBODIES, SERUM<br />

Current as of January 3, 2013 2:22 pm CST 800-533-1710 or 507-266-5700 or <strong>Mayo</strong><strong>Medical</strong>Laboratories.com Page 1281

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