Program - Society of Toxicology

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50 th Anniversary Annual Meeting and ToxExpo Program Description (Continued) MONday Abstract # Abstract # #245 Poster Board Number.....................................427 PATHWAY DIRECTED MOLECULAR ANALYSIS OF LARGE INTESTINAL TUMORS INDUCED IN FISHER 344 RATS EXPOSED TO ALOE VERA WHOLE LEAF EXTRACT IN DRINKING WATER. A. R. Pandiri 1,2 , R. C. Sills 1 , M. J. Hoenerhoff 1 , T. T. Ton 1 , H. L. Hong 1 , G. P. Flake 1 , D. E. Malarkey 1 , I. Pogribny 4 , N. J. Walker 3 and M. D. Boudreau 4 . 1 Cellular and Molecular Pathology Branch, National Toxicology Program (NTP), National Institute of Environmental Health Sciences (NIEHS), Research Triangle Park, NC, 2 Experimental Pathology Laboratories, Inc., Research Triangle Park, NC, 3 NTP/NIEHS, Research Triangle Park, NC and 4 National Center for Toxicological Research, Jefferson, AR. #246 Poster Board Number.....................................428 EFFECTS OF CHRONIC ACRYLAMIDE EXPOSURE ON SYSTEMIC HORMONAL ENVIRONMENT AND CARCINOGENIC TARGET ORGANS IN F344 FEMALE RATS. T. Imai 1 , T. Watari 1 , T. Hayakawa 2 and T. Kitahashi 1 . 1 Central Animal Laboratory, National Cancer Center Research Institute, Tokyo, Japan and 2 Cancer Prevention Basic Research Project, National Cancer Center Research Institute, Tokyo, Japan. Sponsor: A. Nishikawa. #247 Poster Board Number.....................................429 CO-CARCINOGENESIS OF N, N-DIETHYLNITROSAMINE AND CARBON TETRACHLORIDE IN MOUSE LIVER. G. Ainslie 1 , T. Uehara 1 , O. Kosyk 1 , B. Bradford 1 , G. Boorman 2 and I. Rusyn 1 . 1 Department of Environmental Sciences and Engineering, University of North Carolina at Chapel Hill, Chapel Hill, NC and 2 Covance, Princeton, NJ. #248 Poster Board Number.....................................430 KNOCK DOWN OF AHR IN HUMAN BREAST CANCER CELL LINE UPREGULATES THE EXPRESSION OF PROAPOPTOTIC FACTOR BAK. G. Goode and S. E. Eltom. Biochemistry & Cancer Biology, Meharry Medical College, Nashville, TN. #249 Poster Board Number.....................................431 A NOVEL SMALL MOLECULE INHIBITOR OF WNT/β-CATENIN SIGNAL PATHWAY INDUCES CELL CYCLE ARREST IN HUMAN NON-SMALL LUNG CANCER CELLS. J. Choi 1 , S. Lee 1 , Y. Gong 2 , Y. Park 1 and M. Dong 1 . 1 School Lifesciences and Biotechnology, Korea University, Seoul, Republic of Korea and 2 Department of Chemistry, Dongguk University, Seoul, Republic of Korea. Sponsor: B. Lee. #250 Poster Board Number.....................................432 ARISTOLOCHIC ACID NEPHROPATHY: AN ENVIRONMENTAL AND IATROGENIC DISEASE. A. Grollman 1 , B. Jelakovic 2 , Y. Pu 3 and C. Chen 3 . 1 State University of New York at Stony Brook, Stony Brook, NY, 2 University of Zagreb, Zagreb, Croatia and 3 National Taiwan University, Taiwan, China. Sponsor: J. Swenberg. Monday Morning, March 7 9:30 AM to 12:30 PM Exhibit Hall Poster Session: Inflammatory Mediators in Disease Pathogenesis Chairperson(s): Saurabh Chatterjee, NIEHS, Research Triangle Park, NC. Displayed: 9:30 AM–12:30 PM Author Attended: 11:00 AM–12:30 PM #251 Poster Board Number.....................................435 VITAMIN E DEFICIENCY IN MICE TREATED WITH DICHLOROACETATE OR TRICHLOROACETATE MODULATES THE BIOMARKERS OF PHAGOCYTIC ACTIVATION AND ANTIOXIDANT ENZYME ACTIVITIES IN THE PERITONEAL LAVAGE CELLS. E. Hassoun and A. Al-Dieri. Pharmacology, Pharmacy, University of Toledo, Toledo, OH. #252 Poster Board Number.....................................436 XENOBIOTIC-INDUCED ENDOPLASMIC RETICULUM STRESS TRIGGERS PRO- INFLAMMATORY NF-κB SIGNALS VIA REPRESSION OF PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR γ. Y. Moon and S. Park. Microbiology and Immunology, Pusan National University School of Medicine and Medical Research Institute, Yangsan, Republic of Korea. #253 Poster Board Number.....................................437 PRO-INFLAMMATORY CYTOKINE AND COMPLEMENT RECEPTOR 3 (CR3) RESPONSES TO FUNGAL CELL WALL MANNAN AND MANNAN BINDING LECTIN (MBL) IN HUMAN WHOLE BLOOD AND MONOCYTES. A. M. Nilsen 1 , I. Rauk 1 , M. Løvik 1,2 and L. N. Johannessen 1 . 1 Cancer Research and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway and 2 Division of Environmental Medicine, Norwegian Institute of Public Health, Oslo, Norway. #254 Poster Board Number.....................................438 ANTIBACTERIAL AGENT TRICLOSAN INHIBITS IgE RECEPTOR-MEDIATED MAST CELL DEGRANULATION. R. K. Palmer 1,2 , B. Burpee 2 , L. Hutchinson 2 , Z. Kormendy 2 , E. Tupper 2 , J. Pelletier 2 , E. Malay 2 and J. A. Gosse 1,2 . 1 Graduate School of Biomedical Sciences, University of Maine, Orono, ME and 2 Molecular and Biomedical Sciences, University of Maine, Orono, ME. #255 Poster Board Number.....................................439 TRANSACTIVATION OF GENE EXPRESSION BY NFκB IS DEPENDENT ON THIOREDOXIN REDUCTASE ACTIVITY. W. Watson and J. Heilman. Department of Medicine/GI, University of Louisville, Louisville, KY. 136 Education-Career Development Sessions Exhibitor Hosted Sessions Featured Sessions Historical Highlights Informational Sessions Platform Sessions
Society of Toxicology 2011 Program Description (Continued) Abstract # #256 Poster Board Number.....................................440 TLR3 PROTECTS AGAINST MYOCARDITIS BY PROMOTING A TH1 RESPONSE, DECREASING VIRAL REPLICATION, PREVENTING SYSTOLIC FAILURE. E. Abston, A. Bucek, A. Frisancho, M. Coronado, J. Shin and D. Fairweather. Environmental Health Sciences, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD. #257 Poster Board Number.....................................441 S-NITROSYLATION OF SURFACTANT PROTEIN-D OCCURS IN BLEOMYCIN- INDUCED INJURY AND IS A PRO-INFLAMMATORY MEDIATOR VIA ACTIVATION OF NF-κB DEPENDENT PATHWAYS. C. Guo and A. Gow. Pharmacology & Toxicology, Rutgers University, Piscataway, NJ. #258 Poster Board Number.....................................442 UTILIZATION OF EXTRACELLULAR GLUTATHIONE BY PHAGOCYTOSIS REDUCES TUMOR NECROSIS FACTOR α RELEASE IN MACROPHAGES. N. S. Gould 1,2 , E. Min 1 and B. J. Day 1,2,3 . 1 Medicine, National Jewish Health, Denver, Co., 2 Pharmaceutical Sciences, University of Colorado AMC, Aurora, CO and 3 Immunology, University of Colorado AMC, Aurora, CO. #259 Poster Board Number.....................................443 ACROLEIN INHIBITS THE CLEAVAGE OF ADHESION MOLECULES IN CYTOKINE- STIMULATED ENDOTHELIAL CELLS. S. D. Sithu, A. Bhatnagar, S. Srivastava and S. E. D’Souza. School of Medicine, University of Louisville, Louisville, KY. #260 Poster Board Number.....................................444 INDUCTION OF PROINFLAMMATORY MEDIATORS FACILITATES PCB- MEDIATED ENHANCEMENT OF BRAIN METASTASIS FORMATION. E. Bodone Sipos, L. Chen, I. Andras, B. Zhang, J. Wrobel, M. Park, J. Choi, S. Eum and M. Toborek. Molecular Neuroscience and Vascular Laboratory, Department of Neurosurgery, University of Kentucky, Lexington, KY. #261 Poster Board Number.....................................445 NITRIC OXIDE ENHANCES BACTERIAL CLEARANCE IN HYPEROXIA. A. Gore. St. John’s University, Queens, NY. #262 Poster Board Number.....................................446 ENDOTHELIAL ACTIVATION BY 4, HYDROXY TRANS-2-NONENAL: ROLE OF ENDOPLASMIC RETICULUM STRESS. E. N. Vladykovskaya, S. D. Sithu, P. Haberzettl, N. S. Wickramasinghe, O. A. Barski, S. E. D’Souza, A. Bhatnagar and S. Srivastava. School of Medicine, University of Louisville, Louisville, KY. #263 Poster Board Number.....................................447 LOVASTATIN ATTENUATES HYPEROXIA- INDUCED HMGB1 RELEASE AND RESCUES MACROPHAGE FUNCTION VIA INACTIVATION OF NF-κB P65 PATHWAY. R. Malla 1 and L. Mantell 1,2 . 1 St. John’s University, Queens, NY and 2 The Feinstein Institute for Medical Research, North Shore-LIJ Health System, Manhasset, NY. Abstract # #264 Poster Board Number.....................................448 SELECTIVE ALPHA7 NICOTINIC ACETYLCHOLINE RECEPTOR AGONIST GTS-21 ENHANCES HYPEROXIC MACROPHAGE FUNCTION. R. A. Sitapara. Department of Pharmaceutical Sciences, St. Johns University, Jamaica, NY. Sponsor: L. Mantell. Monday Morning, March 7 9:30 AM to 12:30 PM Exhibit Hall Poster Session: Metals I Chairperson(s): Jaclyn Goodrich, University of Michigan, Ann Arbor, MI. Displayed: 9:30 AM–12:30 PM Author Attended: 9:30 AM–11:00 AM #265 Poster Board Number.....................................501 METALLOTHIONEIN AND ACUTE CADMIUM-INDUCED DNA OXIDATIVE DAMAGE. W. Qu 1 , L. Cheng 1 , Y. Sun 1 , R. P. Mason 2 and M. Waalkes 1 . 1 NTP Laboratories, NTP, NIEHS, Research Triangle Park, NC and 2 Laboratory of Toxicology and Pharmacology, NIEHS, Research Triangle Park, NC. #266 Poster Board Number.....................................502 SEXUAL DIMORPHISM OF CADMIUM- INDUCED TOXICITY IN RATS: INVOLVEMENT OF PROGESTERONE. H. Shimada 1 , T. Hashiguchi 1 , A. Yasutake 2 , M. P. Waalkes 3 and Y. Imamura 4 . 1 Kumamoto University, Kumamoto, Japan, 2 National Institute for Minamata Disease, Kumamoto, Japan, 3 NIEHS, Research Triangle Park, NC and 4 Nihon Pharmaceutical University, Saitama, Japan. #267 Poster Board Number.....................................503 CADMIUM ACCUMULATES WITHIN PANCREATIC ISLETS RESULTING IN IMPAIRED GLUCOSE STIMULATED INSULIN SECRETION IN AN ANIMAL MODEL OF SUBCHRONIC EXPOSURE. J. Edwards, R. Fitzgerald and A. Olsen. Department of Pharmacology, Midwestern University, Downers Grove, IL. #268 Poster Board Number.....................................504 CADMIUM ALTERS MICRORNA EXPRESSION IN HUMAN A549 ALVEOLAR EPITHELIAL CELLS. M. J. Fay, P. Rodriguez, L. A. Alt and W. C. Prozialeck. Pharmacology, Midwestern University, Downers Grove, IL. #269 Poster Board Number.....................................505 SUPPRESSION OF IRON TRANSPORT SYSTEM IN DUODENUM BY CADMIUM. M. Satoh, H. Banno and Y. Fujiwara. Laboratory of Pharmaceutical Health Sciences, School of Pharmacy, Aichi Gakuin University, Nagoya, Japan. MONday Poster Sessions Regional Interest Session Roundtable Sessions Symposium Sessions Thematic Sessions Workshop Sessions 137
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50 th Anniversary Annual Meeting &
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Scientific Program Overview A page
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9:00 AM-12:30 PM POSTER SESSionS
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March 6-10, 2011 Walter E. Washingt
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Celebration Activities Historical H
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of the Society Regional Chapter Yea
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SOT Presidents 1961-2011 1966 1967
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The SOT Council Thanks and Recogniz
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of the Past 50 Years 2003 Michael D
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Thank You to the following individu
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SOT Celebration Event Floor Plan Ba
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50 th Anniversary Annual Meeting an
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Toxicological Sciences The Official
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Society of Toxicology 2011 Walter E
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Society of Toxicology 2011 Washingt
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2011 SOT 50 th Anniversary Featured
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Society of Toxicology 2011 ToxExpo
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Society of Toxicology 2011 Exhibito
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Creating a Safer and Healthier Worl
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Society of Toxicology 2011 General
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SOT Job Bank YOUR RECRUITMENT AND E
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Society of Toxicology 2011 SOT 2011
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Society of Toxicology 2011 Recognit
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Society of Toxicology 2011 Recognit
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Society of Toxicology 2011 Author I
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Society of Toxicology 2011 2010-201
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Society of Toxicology 2011 Elected
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